Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.34 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | ORAI1 | Q96D31 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.33 |
| ▸ | SSTR5 | P35346 | 1/20 | 0.33 |
| ▸ | MBD2 | Q9UBB5 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16274185 | 0.90 | RECQL (0.43) | RECQLPKMKDM4EMAPTNPC1 | |
| SCHEMBL1611209 | 0.88 | HTT (0.41) | RECQLPKMPOLBKDM4ESSTR5 | |
| SCHEMBL3648777 | 0.88 | RECQL (0.34) | RECQLCA1CA2PKMKDM4E | |
| SCHEMBL28551536 | 0.87 | RECQL (0.38) | RECQLNLRP3CA1CA2CHRNB4 | |
| SCHEMBL588568 | 0.87 | RECQL (0.36) | RECQLCA1CA2PKMNPC1 | |
| SCHEMBL3123277 | 0.87 | HTT (0.43) | RECQLNLRP3PKMKDM4EMAPT | |
| SCHEMBL28971266 | 0.87 | RECQL (0.36) | RECQLCA1CA2PKMKDM4E | |
| SCHEMBL1611047 | 0.87 | RECQL (0.36) | RECQLPKM | |
| SCHEMBL566200 | 0.86 | RECQL (0.38) | RECQLNLRP3CA1CA2POLB | |
| SCHEMBL472744 | 0.86 | CA1 (0.37) | RECQLCA1CA2PKMPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2181100-A2 | INSECTICIDAL ARYL ISOXAZOLINE DERIVATIVES | Bayer CropScience AG (DE) | 2010-05-05 | — | — | EP | disclosed |
| US-20080262057-A1 | Diarylisoxazolines | DOW AGROSCIENCES LLC (US) | 2008-10-23 | — | — | US | disclosed |
| WO-2008122375-A2 | INSECTICIDAL ARYL ISOXAZOLINE DERIVATIVES | BAYER CROPSCIENCE AG (DE) | 2008-10-16 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080262057-A1 | Diarylisoxazolines | DDT, PRDX1, ACHE | RECQL 1200/4885NLRP3 3665/4885CA1 1439/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.