Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | ADRA1D | P25100 | 6/20 | 0.37 |
| ▸ | ADRA1A | P35348 | 6/20 | 0.37 |
| ▸ | ADRA1B | P35368 | 6/20 | 0.37 |
| ▸ | CASP3 | P42574 | 1/20 | 0.37 |
| ▸ | PRKDC | P78527 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12489682 | 0.92 | KDM4E (0.39) | PKMTSHRKMT2ASMN1; SMN2ADRA1D | |
| SCHEMBL1305247 | 0.87 | GRM5 (0.33) | PKMTSHRKMT2ASMN1; SMN2 | |
| SCHEMBL981067 | 0.81 | MAPT (0.34) | PKMTSHRKMT2ASMN1; SMN2 | |
| SCHEMBL1858613 | 0.81 | RECQL (0.34) | PKMKMT2A | |
| SCHEMBL3695100 | 0.81 | RECQL (0.44) | PKMTSHRSMN1; SMN2 | |
| SCHEMBL1856768 | 0.80 | TAAR1 (0.35) | PKM | |
| SCHEMBL1858126 | 0.80 | SSTR5 (0.39) | PKMKMT2A | |
| SCHEMBL3111479 | 0.80 | RECQL (0.34) | PKM | |
| SCHEMBL16274185 | 0.79 | RECQL (0.43) | PKMKMT2ASMN1; SMN2 | |
| SCHEMBL3116710 | 0.79 | KDM4E (0.35) | PKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8372867-B2 | Insecticidal aryl isoxazoline derivatives | BAYER CROPSCIENCE AG (DE) | 2013-02-12 | — | — | US | disclosed |
| US-8372867-B2 | Insecticidal aryl isoxazoline derivatives | BAYER CROPSCIENCE AG (DE) | 2013-02-12 | — | — | US | disclosed |
| US-8242283-B2 | Isoxazoline compound and pesticide | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 2012-08-14 | — | — | US | disclosed |
| US-20110172414-A1 | ISOXAZOLINE COMPOUND AND PESTICIDE | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 2011-07-14 | — | — | US | disclosed |
| US-7947715-B2 | Isoxazoline compound and pesticide | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 2011-05-24 | — | — | US | disclosed |
| US-20100179194-A1 | INSECTICIDAL ARYL ISOXAZOLINE DERIVATIVES | BAYER CORPSCIENCE AG (DE) | 2010-07-15 | — | — | US | disclosed |
| US-20100179194-A1 | INSECTICIDAL ARYL ISOXAZOLINE DERIVATIVES | BAYER CORPSCIENCE AG (DE) | 2010-07-15 | — | — | US | disclosed |
| EP-1997813-B1 | SUBSTITUTED ISOXAZOLINE COMPOUND AND PEST CONTROL AGENT | NISSAN CHEMICAL IND LTD (JP) | 2010-05-05 | — | — | EP | disclosed |
| EP-2181100-A2 | INSECTICIDAL ARYL ISOXAZOLINE DERIVATIVES | Bayer CropScience AG (DE) | 2010-05-05 | — | — | EP | disclosed |
| US-20090156643-A1 | Substituted isoxazoline compound and pesticide | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 2009-06-18 | — | — | US | disclosed |
| EP-1997813-A1 | SUBSTITUTED ISOXAZOLINE COMPOUND AND PEST CONTROL AGENT | Nissan Chemical Industries, Ltd. (JP) | 2008-12-03 | — | — | EP | disclosed |
| WO-2008122375-A2 | INSECTICIDAL ARYL ISOXAZOLINE DERIVATIVES | BAYER CROPSCIENCE AG (DE) | 2008-10-16 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100179194-A1 | INSECTICIDAL ARYL ISOXAZOLINE DERIVATIVES | CYP4X1, AADAC, CYP3A7 | PKM 2952/4885TSHR 953/4885KMT2A 1160/4885 |
| US-20110172414-A1 | ISOXAZOLINE COMPOUND AND PESTICIDE | HCRTR1, HAX1, CHRM1 | PKM 4739/4885TSHR 569/4885KMT2A 1090/4885 |
| US-20090156643-A1 | Substituted isoxazoline compound and pesticide | HCRTR1, CBR1, CHRM1 | PKM 4737/4885TSHR 770/4885KMT2A 843/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.