SCHEMBL12490002

SCHEMBL12490002

CNc1occ2ccccc12

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.37
TSHR P16473 3/20 0.37
HSD17B10 Q99714 3/20 0.37
ALOX15 P16050 3/20 0.37
KMT2A Q03164 3/20 0.37
MEN1 O00255 2/20 0.37
KDM4E B2RXH2 2/20 0.37
GAA P10253 2/20 0.37
HPGD P15428 2/20 0.37
HCRTR1 O43613 1/20 0.37
GLA P06280 1/20 0.37
POLB P06746 1/20 0.37
ALOX12 P18054 1/20 0.37
CASP1 P29466 1/20 0.37
CASP7 P55210 1/20 0.37
HTT P42858 1/20 0.36
NUDT1 P36639 1/20 0.35
CYP2A6 P11509 2/20 0.35
TDP1 Q9NUW8 2/20 0.35
ELANE P08246 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL27880883 0.98 ALDH1A1 (0.36) ALDH1A1TSHRHSD17B10ALOX15KMT2A
SCHEMBL29196014 0.82 ALDH1A1 (0.38) ALDH1A1TSHRHSD17B10ALOX15KDM4E
SCHEMBL971315 0.78 KDM4E (0.41) ALDH1A1TSHRHSD17B10ALOX15KDM4E
Hydrochloric Acid SCHEMBL20542638 0.76 KDM4E (0.40) ALDH1A1TSHRHSD17B10ALOX15KDM4E
SCHEMBL6586906 0.74 ALDH1A1 (0.39) ALDH1A1TSHRHSD17B10KMT2AMEN1
SCHEMBL29364943 0.71 RAB9A (0.58) ALDH1A1KMT2AMEN1KDM4EGAA
SCHEMBL9025710 0.71 CYP1A2 (0.41) ALDH1A1KMT2AMEN1KDM4EGAA
SCHEMBL27290935 0.71 KDM4E (0.46) ALDH1A1TSHRHSD17B10KMT2AMEN1
SCHEMBL29208127 0.70 ABCG2 (0.45) CYP2D6CCR4SLC6A4
SCHEMBL6207194 0.70 ALDH1A1 (0.41) ALDH1A1HSD17B10GAAHTTELANE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-107105667-B Probes for imaging huntingtin CHDI基金会股份有限公司 2021-08-17 CN disclosed
WO-2011082077-A1 HEPATITIS C VIRUS INHIBITORS BRISTOL-MYERS SQUIBB COMPANY (US) 2011-07-07 WO disclosed