SCHEMBL29196014

SCHEMBL29196014

c1ccc2c(Nc3occ4ccccc34)occ2c1

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 8/20 0.38
HSD17B10 Q99714 6/20 0.38
TSHR P16473 4/20 0.38
CYP2A6 P11509 4/20 0.38
TDP1 Q9NUW8 1/20 0.38
HPRT1 P00492 1/20 0.35
HPGD P15428 5/20 0.34
CDC25B P30305 2/20 0.34
CYP3A4 P08684 2/20 0.34
TP53 P04637 1/20 0.34
ALOX15 P16050 1/20 0.34
ATM Q13315 1/20 0.34
CCR4 P51679 1/20 0.34
CYP1A2 P05177 3/20 0.32
THRB P10828 2/20 0.32
HIF1A Q16665 2/20 0.32
CYP1B1 Q16678 1/20 0.32
ALOX12 P18054 1/20 0.32
KDM4E B2RXH2 1/20 0.32
APAF1 O14727 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12490002 0.82 ALDH1A1 (0.37) ALDH1A1HSD17B10TSHRCYP2A6TDP1
SCHEMBL29362567 0.81 ALDH1A1 (0.48) ALDH1A1HSD17B10TSHRHPGDCDC25B
SCHEMBL29365326 0.81 NPY5R (0.45) ALDH1A1HPGDTP53ALOX12KDM4E
SCHEMBL29364943 0.78 RAB9A (0.58) ALDH1A1TDP1HPGDCDC25BTP53
SCHEMBL29208127 0.77 ABCG2 (0.45) CCR4MAPTRAB9A
SCHEMBL971315 0.77 KDM4E (0.41) ALDH1A1HSD17B10TSHRHPGDALOX15
SCHEMBL6586906 0.77 ALDH1A1 (0.39) ALDH1A1HSD17B10TSHRCYP2A6TDP1
Hydrochloric Acid SCHEMBL20542638 0.76 KDM4E (0.40) ALDH1A1HSD17B10TSHRHPGDALOX15
SCHEMBL286416 0.68 ALDH1A1 (0.39) ALDH1A1HSD17B10TSHRCYP2A6TDP1
SCHEMBL4079696 0.68 CYP2A6 (0.42) ALDH1A1HSD17B10TSHRCYP2A6TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117616032-A Rare earth complex 东曹株式会社 2024-02-27 CN disclosed