Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.51 |
| ▸ | MAPT | P10636 | 3/20 | 0.51 |
| ▸ | HPGD | P15428 | 3/20 | 0.51 |
| ▸ | RECQL | P46063 | 1/20 | 0.47 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.46 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1128004 | 0.78 | ALDH1A1 (0.47) | ALDH1A1KMT2AMAPTHPGDRECQL | |
| SCHEMBL6164008 | 0.76 | HPGD (0.62) | ALDH1A1KMT2AMAPTHPGDGAA | |
| SCHEMBL10795663 | 0.75 | TSHR (0.54) | ALDH1A1KMT2AMAPTHPGDRECQL | |
| SCHEMBL25440184 | 0.74 | KMT2A (0.74) | ALDH1A1KMT2AMAPTHPGDNCOA1 | |
| SCHEMBL23773682 | 0.74 | ALDH1A1 (0.44) | ALDH1A1KMT2AMAPTHPGDRECQL | |
| SCHEMBL10795656 | 0.72 | ALDH1A1 (0.57) | ALDH1A1KMT2AMAPTHPGDGAA | |
| SCHEMBL9196237 | 0.72 | HPGD (0.57) | ALDH1A1KMT2AMAPTHPGDGAA | |
| SCHEMBL9298611 | 0.71 | KMT2A (0.56) | ALDH1A1KMT2AMAPTHPGDGAA | |
| SCHEMBL11179702 | 0.71 | KMT2A (0.46) | ALDH1A1KMT2AMAPTHPGDNCOA1 | |
| SCHEMBL25440265 | 0.71 | KMT2A (0.65) | ALDH1A1KMT2AMAPTHPGDGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 71 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250074861-A1 | Anticonvulsant Compounds | OWEN BARRY PHARMACEUTICALS INC (CA) | 2025-03-06 | — | — | US | disclosed |
| US-20250011333-A1 | PYRAZOLO-QUINAZOLINE DERIVATIVES, PROCESS FOR THEIR PREPARATION AND THEIR USE AS KINASE INHIBITORS | NERVIANO MEDICAL SCIENCES SRL (IT) | 2025-01-09 | — | — | US | disclosed |
| US-11952338-B2 | Anticonvulsant compounds | OWEN-BARRY PHARMACEUTICALS INC. (CA) | 2024-04-09 | — | — | US | disclosed |
| US-11345652-B2 | Anticonvulsant compounds | OWEN-BARRY PHARMACEUTICALS (CA) | 2022-05-31 | — | — | US | disclosed |
| US-11345652-B2 | Anticonvulsant compounds | OWEN-BARRY PHARMACEUTICALS (CA) | 2022-05-31 | — | — | US | disclosed |
| US-20210300935-A1 | PYRAZOLO-QUINAZOLINE DERIVATIVES, PROCESS FOR THEIR PREPARATION AND THEIR USE AS KINASE INHIBITORS | Nerviano Medical Sciences, S.R.L. (IT) | 2021-09-30 | — | — | US | disclosed |
| US-20210300935-A1 | PYRAZOLO-QUINAZOLINE DERIVATIVES, PROCESS FOR THEIR PREPARATION AND THEIR USE AS KINASE INHIBITORS | Nerviano Medical Sciences, S.R.L. (IT) | 2021-09-30 | — | — | US | disclosed |
| US-20210017116-A1 | ANTICONVULSANT COMPOUNDS | OWEN-BARRY PHARMACEUTICALS INC. (CA) | 2021-01-21 | — | — | US | disclosed |
| US-20210017116-A1 | ANTICONVULSANT COMPOUNDS | OWEN-BARRY PHARMACEUTICALS INC. (CA) | 2021-01-21 | — | — | US | disclosed |
| US-20200148623-A1 | ANTICONVULSANT COMPOUNDS | OWEN-BARRY PHARMACEUTICALS INC. (CA) | 2020-05-14 | — | — | US | disclosed |
| US-7482354-B2 | Pyrazolo-quinazoline derivatives, process for their preparation and their use as kinase inhibitors | NERVIANO MEDICAL SCIENCES S.R.L. (IT) | 2009-01-27 | — | — | US | disclosed |
| US-7482354-B2 | Pyrazolo-quinazoline derivatives, process for their preparation and their use as kinase inhibitors | NERVIANO MEDICAL SCIENCES S.R.L. (IT) | 2009-01-27 | — | — | US | disclosed |
| US-7482354-B2 | Pyrazolo-quinazoline derivatives, process for their preparation and their use as kinase inhibitors | NERVIANO MEDICAL SCIENCES S.R.L. (IT) | 2009-01-27 | — | — | US | disclosed |
| EP-1853578-A1 | SUBSTITUTED TETRALINS AS SELECTIVE ESTROGEN RECEPTOR-BETA AGONISTS | ELI LILLY AND COMPANY (US) | 2007-11-14 | — | — | EP | disclosed |
| US-20070185143-A1 | Pyrazolo-quinazoline derivatives, process for their preparation and their use as kinase inhibitors | NERVIANO MEDICAL SCIENCES S.R.L. (IT) | 2007-08-09 | — | — | US | disclosed |
| US-20070185143-A1 | Pyrazolo-quinazoline derivatives, process for their preparation and their use as kinase inhibitors | NERVIANO MEDICAL SCIENCES S.R.L. (IT) | 2007-08-09 | — | — | US | disclosed |
| US-20070185143-A1 | Pyrazolo-quinazoline derivatives, process for their preparation and their use as kinase inhibitors | NERVIANO MEDICAL SCIENCES S.R.L. (IT) | 2007-08-09 | — | — | US | disclosed |
| WO-2006088716-A1 | SUBSTITUTED TETRALINS AS SELECTIVE ESTROGEN RECEPTOR-BETA AGONISTS | ELI LILLY AND COMPANY (US) | 2006-08-24 | — | — | WO | disclosed |
| EP-1636236-A1 | PYRAZOLO-QUINAZOLINE DERIVATIVES,PROCESS FOR THEIR PREPARATION AND THEIR USE AS KINASE INHIBITORS | Pharmacia Italia S.p.A. (IT) | 2006-03-22 | — | — | EP | disclosed |
| WO-2004104007-A1 | PYRAZOLO-QUINAZOLINE DERIVATIVES,PROCESS FOR THEIR PREPARATION AND THEIR USE AS KINASE INHIBITORS | PHARMACIA ITALIA S.P.A. (IT) | 2004-12-02 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210300935-A1 | PYRAZOLO-QUINAZOLINE DERIVATIVES, PROCESS FOR THEIR PREPARATION AND THEIR USE AS KINASE INHIBITORS | MAP3K5, MAP3K9, MAP4K2 | ALDH1A1 3081/4885KMT2A 1627/4885MAPT 2476/4885 |
| US-11952338-B2 | Anticonvulsant compounds | GABRE, CACNA1B, GRIK5 | ALDH1A1 1140/4885KMT2A 2288/4885MAPT 1725/4885 |
| US-20210017116-A1 | ANTICONVULSANT COMPOUNDS | GABRE, CACNA1B, GRIK5 | ALDH1A1 1140/4885KMT2A 2288/4885MAPT 1725/4885 |
| US-20250011333-A1 | PYRAZOLO-QUINAZOLINE DERIVATIVES, PROCESS FOR THEIR PREPARATION AND THEIR USE AS KINASE INHIBITORS | MAP3K5, MAP3K9, MAP4K2 | ALDH1A1 3081/4885KMT2A 1627/4885MAPT 2476/4885 |
| US-20070185143-A1 | Pyrazolo-quinazoline derivatives, process for their preparation and their use as kinase inhibitors | MAP3K5, MAP3K9, MAP3K19 | ALDH1A1 3008/4885KMT2A 1394/4885MAPT 1972/4885 |
| US-20200148623-A1 | ANTICONVULSANT COMPOUNDS | GABRE, CACNA1B, GRIK5 | ALDH1A1 1140/4885KMT2A 2288/4885MAPT 1725/4885 |
| US-11345652-B2 | Anticonvulsant compounds | GABRE, CACNA1B, GRIK5 | ALDH1A1 1140/4885KMT2A 2288/4885MAPT 1725/4885 |
| US-20250074861-A1 | Anticonvulsant Compounds | GABRE, CACNA1B, GRIK5 | ALDH1A1 1140/4885KMT2A 2288/4885MAPT 1725/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.