Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 5/20 | 0.62 |
| ▸ | MAPT | P10636 | 4/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.62 |
| ▸ | GAA | P10253 | 5/20 | 0.45 |
| ▸ | LMNA | P02545 | 3/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10795656 | 0.81 | ALDH1A1 (0.57) | HPGDMAPTKMT2AALDH1A1GAA | |
| SCHEMBL9196237 | 0.81 | HPGD (0.57) | HPGDMAPTKMT2AALDH1A1GAA | |
| SCHEMBL11791375 | 0.80 | MAPT (0.44) | HPGDMAPTKMT2AALDH1A1GAA | |
| SCHEMBL9298611 | 0.80 | KMT2A (0.56) | HPGDMAPTKMT2AALDH1A1GAA | |
| SCHEMBL25440299 | 0.78 | KMT2A (0.76) | HPGDMAPTKMT2AALDH1A1GAA | |
| SCHEMBL25440183 | 0.77 | MAPT (0.78) | HPGDMAPTKMT2AALDH1A1GAA | |
| SCHEMBL25440072 | 0.77 | KMT2A (1.00) | HPGDMAPTKMT2AALDH1A1GAA | |
| SCHEMBL124904 | 0.76 | ALDH1A1 (0.51) | HPGDMAPTKMT2AALDH1A1GAA | |
| SCHEMBL14501302 | 0.76 | KMT2A (0.52) | HPGDMAPTKMT2AALDH1A1GAA | |
| SCHEMBL2027720 | 0.76 | MAPT (1.00) | HPGDMAPTKMT2AALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1177185-B1 | 4, 5, 6, 7-TETRAHYDROINDAZOLE DERIVATIVES AS ANTITUMOR AGENTS | PHARMACIA ITALIA SPA (IT) | 2005-04-20 | — | — | EP | disclosed |
| US-6716856-B1 | CELL PROLIFERATIVE DISORDERS OR ALZHEIMER'S DISEASE; REDUCED TOXICITY; CDK/CYCLIN KINASE INHIBITORY ACTIVITY | PHARMACIA & TUBJOHN SPA (IT) | 2004-04-06 | — | — | US | disclosed |