Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 4/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.57 |
| ▸ | MAPT | P10636 | 3/20 | 0.57 |
| ▸ | GAA | P10253 | 3/20 | 0.42 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | ELANE | P08246 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14501302 | 0.81 | KMT2A (0.52) | HPGDKMT2AALDH1A1MAPTGAA | |
| SCHEMBL6164008 | 0.81 | HPGD (0.62) | HPGDKMT2AALDH1A1MAPTGAA | |
| SCHEMBL14501327 | 0.79 | KMT2A (0.47) | HPGDKMT2AALDH1A1MAPTGAA | |
| SCHEMBL10795656 | 0.77 | ALDH1A1 (0.57) | HPGDKMT2AALDH1A1MAPTGAA | |
| SCHEMBL9298611 | 0.75 | KMT2A (0.56) | HPGDKMT2AALDH1A1MAPTGAA | |
| SCHEMBL14501278 | 0.75 | GAA (0.50) | HPGDKMT2AALDH1A1MAPTGAA | |
| SCHEMBL25440299 | 0.74 | KMT2A (0.76) | HPGDKMT2AALDH1A1MAPTGAA | |
| SCHEMBL25440072 | 0.73 | KMT2A (1.00) | HPGDKMT2AALDH1A1MAPTGAA | |
| SCHEMBL25440183 | 0.73 | MAPT (0.78) | HPGDKMT2AALDH1A1MAPTGAA | |
| SCHEMBL124904 | 0.72 | ALDH1A1 (0.51) | HPGDKMT2AALDH1A1MAPTGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11168088-B2 | Pyridylamino substituted heterotricyclic compounds, and preparation method and pharmaceutical use thereof | SHANGHAI HAIYAN PHARMACEUTICAL TECHNOLOGY CO., LTD. | 2021-11-09 | — | — | US | disclosed |
| US-20200039983-A1 | PYRIDYLAMINO SUBSTITUTED HETEROTRICYCLIC COMPOUNDS, AND PREPARATION METHOD AND PHARMACEUTICAL USE THEREOF | SHANGHAI HAIYAN PHARMACEUTICAL TECHNOLOGY CO., LTD. (CN) | 2020-02-06 | — | — | US | disclosed |
| EP-0436630-B1 | POLYMER-SUPPORTED 4-(N-BENZYL-N-METHYLAMINO)PYRIDINE CATALYST AND PROCESS FOR SAME | REILLY IND INC (US) | 1995-12-20 | — | — | EP | disclosed |
| US-5229479-A | Polymer-supported 4-(N-benzyl-N-methylamino)pyridine catalyst and process for same | REILLY INDUSTRIES, INC. (US) | 1993-07-20 | — | — | US | disclosed |
| US-5183895-A | 4-(N-benzyl-N-methylamino)pyridine acid salts and use in preparation of polymer-supported catalysts | REILLY INDUSTRIES, INC. (US) | 1993-02-02 | — | — | US | disclosed |
| US-5147954-A | 4-(N-benzyl-N-methylamino)pyridine acid salts and use in preparation of polymer-supported catalysts | REILLY INDUSTRIES INC. (US) | 1992-09-15 | — | — | US | disclosed |
| EP-0436630-A1 | POLYMER-SUPPORTED 4-(N-BENZYL-N-METHYLAMINO)PYRIDINE CATALYST AND PROCESS FOR SAME. | REILLY IND INC (US) | 1991-07-17 | — | — | EP | disclosed |
| EP-0435932-A1 | 4-(N-BENZYL-N-METHYLAMINO)PYRIDINE ACID SALTS AND USE IN PREPARATION OF POLYMER-SUPPORTED CATALYSTS | REILLY INDUSTRIES, INC. (US) | 1991-07-10 | — | — | EP | disclosed |
| US-5015706-A | Polymer-supported 4-(N-benzyl-N-methylamino)pyridine catalyst and process for same | REILLY INDUSTRIES, INC., (US) | 1991-05-14 | — | — | US | disclosed |
| US-4968806-A | 4-(N-benzyl-N-methylamino)pyridine acid salts and use in preparation of polymer-supported catalysts | REILLY INDUSTRIES, INC. (US) | 1990-11-06 | — | — | US | disclosed |
| WO-1990003367-A2 | 4-(N-BENZYL-N-METHYLAMINO)PYRIDINE ACID SALTS AND USE IN PREPARATION OF POLYMER-SUPPORTED CATALYSTS | REILLY INDUSTRIES, INC. (US) | 1990-04-05 | — | — | WO | disclosed |
| WO-1990003368-A2 | POLYMER-SUPPORTED 4-(N-BENZYL-N-METHYLAMINO)PYRIDINE CATALYST AND PROCESS FOR SAME | REILLY INDUSTRIES, INC. (US) | 1990-04-05 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11168088-B2 | Pyridylamino substituted heterotricyclic compounds, and preparation method and pharmaceutical use thereof | CYP2D6, PNPO, CYP2B6 | HPGD 109/4885KMT2A 2962/4885ALDH1A1 2155/4885 |
| US-20200039983-A1 | PYRIDYLAMINO SUBSTITUTED HETEROTRICYCLIC COMPOUNDS, AND PREPARATION METHOD AND PHARMACEUTICAL USE THEREOF | CYP2D6, PNPO, CYP2B6 | HPGD 109/4885KMT2A 2962/4885ALDH1A1 2155/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.