SCHEMBL1249196

SCHEMBL1249196

C1COC(N2CCOCC2)N1

nearest known ligand 0.34

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
CYP2A13 Q16696 1/20 0.34
ALDH1A1 P00352 1/20 0.34
HPGD P15428 1/20 0.34
L3MBTL1 Q9Y468 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27734144 0.88
SCHEMBL28143169 0.87 L3MBTL1 (0.32) L3MBTL1
SCHEMBL4854880 0.84 HTR6 (0.30)
SCHEMBL4080655 0.82
SCHEMBL446064 0.82
SCHEMBL27778680 0.75 HTR6 (0.33)
SCHEMBL3381802 0.74
SCHEMBL6601682 0.71
SCHEMBL24581554 0.67 MEN1 (0.42) CYP2A13ALDH1A1HPGDL3MBTL1SMN1; SMN2
SCHEMBL23097056 0.65

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 65 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110520422-B Novel pyridonecarboxylic acid derivative or salt thereof 涌永制药株式会社 2023-09-05 CN disclosed
EP-3523291-A1 CYANO-SUBSTITUTED HETEROCYCLES WITH ACTIVITY AS INHIBITORS OF USP30 Mission Therapeutics Limited (GB) 2019-08-14 EP disclosed
WO-2018065768-A1 CYANO-SUBSTITUTED HETEROCYCLES WITH ACTIVITY AS INHIBITORS OF USP30 MISSION THERAPEUTICS LIMITED (GB) 2018-04-12 WO disclosed
EP-2464693-B1 AFTER CLEARING AGENT HUNTSMAN ADV MAT SWITZERLAND (CH) 2015-01-28 EP disclosed
US-8575135-B2 Antiviral compounds GILEAD SCIENCES, INC. (US) 2013-11-05 US disclosed
CN-103328480-A Condensed imidazolylimidazoles as antiviral compounds GILEAD SCIENCES INC 2013-09-25 CN disclosed
CN-101784548-B Purine derivatives and their use as modulators of Toll-like receptor 7 GILEAD SCIENCES INC 2013-07-17 CN disclosed
US-20130177530-A1 ANTIVIRAL COMPOUNDS GILEAD SCIENCES, INC. (US) 2013-07-11 US disclosed
CN-101490023-B Modulators of the Pharmacokinetic Properties of Therapeutic Agents GILEAD SCIENCES INC 2013-05-29 CN disclosed
CN-103052631-A Methods and compounds for treating paramyxoviridae virus infections GILEAD SCIENCES INC 2013-04-17 CN disclosed
CN-1649885-A Cellular Accumulation of Phosphonate Analogs of HIV Protease Inhibitor Compounds and Such Compounds GILEAD SCIENCES INC (US) 2005-08-03 CN disclosed
CN-1501937-A Spiro-pyrimidine-2,4,6-trione metalloproteinase inhibitors �Ʒ� 2004-06-02 CN disclosed
CN-1478093-A Coupling process and intermediates useful for preparing cephalosphorins �Ʒ� 2004-02-25 CN disclosed
CN-1478094-A Process and ester derivatives for the preparation of cephalosporins �Ʒ� 2004-02-25 CN disclosed
CN-1355809-A Immunomodulatory steroids, in particular hemihydrate of 16 alpha-bromoepiandrosterone HOLLIS EDEN PHARMACEUTICALS (US) 2002-06-26 CN disclosed
CN-1064351-C Substituted 2, 3-dihydroindenyleneacetylguanidines, method for the production thereof, use thereof as medicaments or use thereof as diagnostic agents and medicaments containing the same HOECHST AG (DE) 2001-04-11 CN disclosed
CN-1064043-C Process for the preparation of 1, 5-benzothiazepine * derivatives TANABE SEIYAKU CO (JP) 2001-04-04 CN disclosed
CN-1244200-A Nucleotide analogs GILEAD SCIENCES INC (US) 2000-02-09 CN disclosed
CN-1172104-A Substituted 2, 3-dihydroindenyleneacetylguanidines, method for the production thereof, use thereof as medicaments or use thereof as diagnostic agents and medicaments containing the same HOECHST AG (DE) 1998-02-04 CN disclosed
CN-1160713-A Process for the preparation of 1, 5-benzothiazepine * derivatives TANABE SEIYAKU CO (JP) 1997-10-01 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130177530-A1 ANTIVIRAL COMPOUNDS MAVS, EIF2AK2, SARS1 CYP2A13 4289/4885ALDH1A1 3925/4885HPGD 4010/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.