Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.55 |
| ▸ | MYC | P01106 | 2/20 | 0.54 |
| ▸ | WDR5 | P61964 | 2/20 | 0.54 |
| ▸ | MAPT | P10636 | 6/20 | 0.51 |
| ▸ | MEN1 | O00255 | 5/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.51 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.51 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.50 |
| ▸ | LMNA | P02545 | 3/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.50 |
| ▸ | GBA1 | P04062 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.49 |
| ▸ | NPC1 | O15118 | 2/20 | 0.49 |
| ▸ | RAB9A | P51151 | 2/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2315152 | 0.81 | MYC (0.54) | HTTMYCWDR5MAPTMEN1 | |
| SCHEMBL1256622 | 0.81 | MAPT (0.63) | HTTMAPTMEN1KMT2AALOX15 | |
| SCHEMBL31311233 | 0.80 | MPL (0.50) | HTTMYCWDR5MAPTMEN1 | |
| SCHEMBL12495322 | 0.80 | RORB (0.53) | MYCWDR5MAPTMEN1KMT2A | |
| SCHEMBL2186314 | 0.80 | MAPT (0.49) | HTTMYCWDR5MAPTMEN1 | |
| SCHEMBL12490383 | 0.79 | MAPT (0.53) | HTTMYCWDR5MAPTMEN1 | |
| SCHEMBL1802030 | 0.78 | SMN1; SMN2 (0.65) | HTTMYCWDR5MAPTMEN1 | |
| SCHEMBL28651159 | 0.77 | MPL (0.50) | HTTMYCWDR5MAPTMEN1 | |
| SCHEMBL19638079 | 0.77 | MYC (0.57) | MYCWDR5MAPTMEN1KMT2A | |
| SCHEMBL17396363 | 0.77 | MAPT (0.51) | MYCWDR5MAPTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109293652-B | Substituted thiazole derivative and application thereof | 四川科伦博泰生物医药股份有限公司 | 2021-10-22 | — | — | CN | disclosed |
| WO-2012100734-A1 | COMPOUNDS USEFUL AS RETINOID-RELATED ORPHAN RECEPTOR GAMMA MODULATORS | GLAXO GROUP LIMITED (GB) | 2012-08-02 | — | — | WO | disclosed |