Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AMY1A | P0DUB6 | 1/20 | 0.53 |
| ▸ | BACE1 | P56817 | 2/20 | 0.49 |
| ▸ | NFE2L2 | Q16236 | 2/20 | 0.47 |
| ▸ | TUBB1 | Q9H4B7 | 7/20 | 0.46 |
| ▸ | ACHE | P22303 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.43 |
| ▸ | TYR | P14679 | 1/20 | 0.43 |
| ▸ | CXCL12 | P48061 | 1/20 | 0.40 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.40 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.40 |
| ▸ | TUBB | P07437 | 1/20 | 0.40 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.40 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.40 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.40 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12035794 | 0.84 | TYR (0.62) | AMY1ABACE1NFE2L2TUBB1ACHE | |
| SCHEMBL9135637 | 0.83 | TUBB1 (0.65) | NFE2L2TUBB1ALDH1A1MAPK1TSHR | |
| SCHEMBL1687375 | 0.82 | TRPA1 (0.61) | AMY1ABACE1NFE2L2TUBB1ACHE | |
| SCHEMBL16954907 | 0.82 | AMY1A (0.51) | AMY1ABACE1NFE2L2TUBB1ACHE | |
| SCHEMBL22387 | 0.82 | ALDH1A1 (0.68) | AMY1ABACE1NFE2L2ALDH1A1MAPT | |
| SCHEMBL721179 | 0.80 | ALDH1A1 (0.65) | NFE2L2TUBB1ALDH1A1MAPTMAPK1 | |
| SCHEMBL16046759 | 0.79 | BACE1 (0.49) | AMY1ABACE1NFE2L2TUBB1ACHE | |
| SCHEMBL31128655 | 0.77 | AMY1A (0.59) | AMY1ABACE1ACHEALDH1A1MAPT | |
| SCHEMBL29066079 | 0.77 | TUBB1 (0.65) | TUBB1TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL16047644 | 0.77 | BACE1 (0.51) | AMY1ABACE1NFE2L2TUBB1ACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2683697-A1 | SUBSTITUTED MORPHOLINES AS MODULATORS FOR THE CALCIUM SENSING RECEPTOR | Lupin Limited (IN) | 2014-01-15 | — | — | EP | disclosed |
| WO-2012120476-A1 | SUBSTITUTED MORPHOLINES AS MODULATORS FOR THE CALCIUM SENSING RECEPTOR | LUPIN LIMITED (IN) | 2012-09-13 | — | — | WO | disclosed |