Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.38 |
| ▸ | GPR3 | P46089 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.33 |
| ▸ | RORC | P51449 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 2/20 | 0.32 |
| ▸ | CA2 | P00918 | 2/20 | 0.32 |
| ▸ | ACHE | P22303 | 1/20 | 0.32 |
| ▸ | ATM | Q13315 | 2/20 | 0.32 |
| ▸ | NAMPT | P43490 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | RECQL | P46063 | 1/20 | 0.31 |
| ▸ | IDO1 | P14902 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL12498684 | 0.82 | ALDH1A1 (0.43) | LMNAALDH1A1KMT2AMEN1L3MBTL1 | |
| Trifluoromethanesulfonic Acid SCHEMBL847347 | 0.80 | GPR3 (0.40) | GPR3CA1CA2ACHE | |
| Trifluoromethanesulfonic Acid SCHEMBL4187466 | 0.70 | HSD17B10 (0.43) | LMNAALDH1A1KMT2AMEN1TAAR1 | |
| Trifluoromethanesulfonic Acid SCHEMBL3096657 | 0.70 | MAPT (0.37) | LMNAGPR3ALDH1A1KMT2ASMN1; SMN2 | |
| Trifluoromethanesulfonic Acid SCHEMBL31603622 | 0.69 | TDP1 (0.43) | LMNAALDH1A1KMT2ASMN1; SMN2MEN1 | |
| Trifluoromethanesulfonic Acid SCHEMBL3832689 | 0.69 | CA1 (0.40) | ALDH1A1CA1CA2ACHEIDO1 | |
| Trifluoromethanesulfonic Acid SCHEMBL3835272 | 0.69 | KCNH2 (0.40) | ALDH1A1SMN1; SMN2CA1CA2ACHE | |
| Trifluoromethanesulfonic Acid SCHEMBL36383 | 0.68 | GPR3 (0.43) | LMNAGPR3SMN1; SMN2CA1CA2 | |
| SCHEMBL3834477 | 0.68 | CA1 (0.38) | CA1CA2 | |
| Trifluoromethanesulfonic Acid SCHEMBL2945043 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2667709-A1 | HISTONE DEACETYLASE INHIBITORS AND COMPOSITIONS AND METHODS OF USE THEREOF | CHDI Foundation, Inc. (US) | 2013-12-04 | — | — | EP | disclosed |
| WO-2012103008-A1 | HISTONE DEACETYLASE INHIBITORS AND COMPOSITIONS AND METHODS OF USE THEREOF | CHDI FOUNDATION, INC. (US) | 2012-08-02 | — | — | WO | disclosed |