Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDGFRA | P16234 | 3/20 | 0.57 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.57 |
| ▸ | KDR | P35968 | 3/20 | 0.54 |
| ▸ | AXL | P30530 | 5/20 | 0.52 |
| ▸ | FGFR2 | P21802 | 4/20 | 0.52 |
| ▸ | KIT | P10721 | 1/20 | 0.52 |
| ▸ | EGFR | P00533 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1875038 | 0.91 | PDGFRA (0.69) | PDGFRAPDGFRBKDRAXLFGFR2 | |
| SCHEMBL14540582 | 0.90 | PDGFRA (0.60) | PDGFRAPDGFRBKDRAXLFGFR2 | |
| SCHEMBL12663636 | 0.90 | PDGFRA (0.49) | PDGFRAPDGFRBKDRAXLFGFR2 | |
| SCHEMBL13980699 | 0.86 | PDGFRA (0.45) | PDGFRAPDGFRBKDRAXLFGFR2 | |
| SCHEMBL5208153 | 0.85 | PDGFRA (0.56) | PDGFRAPDGFRBKDRAXLFGFR2 | |
| SCHEMBL1894179 | 0.84 | AXL (0.55) | PDGFRAPDGFRBKDRAXLFGFR2 | |
| SCHEMBL12410622 | 0.84 | PDGFRA (0.53) | PDGFRAPDGFRBKDRAXLFGFR2 | |
| SCHEMBL14540589 | 0.84 | MET (0.55) | PDGFRAPDGFRBKDRAXLFGFR2 | |
| SCHEMBL13980801 | 0.84 | PDGFRA (0.60) | PDGFRAPDGFRBKDRFGFR2EGFR | |
| SCHEMBL14139302 | 0.83 | PDGFRA (0.58) | PDGFRAPDGFRBKDRAXLFGFR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7973160-B2 | Nitrogen-containing aromatic derivatives | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2011-07-05 | — | — | US | disclosed |
| US-20100197911-A1 | Nitrogen-Containing Aromatic Derivatives | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2010-08-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100197911-A1 | Nitrogen-Containing Aromatic Derivatives | GNG2, GCG, FRG1 | PDGFRA 3131/4885PDGFRB 3824/4885KDR 2687/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.