Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RY1 | P47900 | 1/20 | 0.75 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.59 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.59 |
| ▸ | MEN1 | O00255 | 6/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.59 |
| ▸ | MAPT | P10636 | 5/20 | 0.59 |
| ▸ | RAB9A | P51151 | 3/20 | 0.59 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.59 |
| ▸ | LMNA | P02545 | 5/20 | 0.57 |
| ▸ | HTT | P42858 | 3/20 | 0.57 |
| ▸ | NPC1 | O15118 | 3/20 | 0.57 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.57 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.57 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.57 |
| ▸ | PDE4A | P27815 | 1/20 | 0.57 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.57 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.57 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.57 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.57 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4345497 | 0.88 | MEN1 (0.74) | P2RY1EPHX2EPHX1MEN1KMT2A | |
| SCHEMBL4347321 | 0.83 | P2RY1 (0.61) | P2RY1EPHX2EPHX1MEN1KMT2A | |
| SCHEMBL4358566 | 0.83 | MEN1 (0.69) | EPHX2EPHX1MEN1KMT2AMAPT | |
| SCHEMBL4341617 | 0.83 | MAOB (0.60) | P2RY1MEN1KMT2AMAPTNPSR1 | |
| SCHEMBL4353624 | 0.82 | P2RY1 (0.68) | P2RY1EPHX2EPHX1MEN1KMT2A | |
| SCHEMBL15786287 | 0.81 | MEN1 (0.76) | P2RY1EPHX2EPHX1MEN1KMT2A | |
| SCHEMBL11357914 | 0.81 | ALDH1A1 (0.59) | P2RY1EPHX2EPHX1MEN1KMT2A | |
| SCHEMBL24272322 | 0.80 | MEN1 (0.70) | P2RY1EPHX2EPHX1MEN1KMT2A | |
| SCHEMBL14758356 | 0.80 | MEN1 (0.75) | P2RY1EPHX2EPHX1MEN1KMT2A | |
| SCHEMBL12499941 | 0.80 | P2RY1 (0.70) | P2RY1EPHX2EPHX1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11583509-B2 | Compound for treating cancer and diabetes | CITY OF HOPE (US) | 2023-02-21 | — | — | US | disclosed |
| US-11583509-B2 | Compound for treating cancer and diabetes | CITY OF HOPE (US) | 2023-02-21 | — | — | US | disclosed |
| US-20220023240-A1 | COMPOUND FOR TREATING CANCER AND DIABETES | CITY OF HOPE | 2022-01-27 | — | — | US | disclosed |
| US-20220023240-A1 | COMPOUND FOR TREATING CANCER AND DIABETES | CITY OF HOPE | 2022-01-27 | — | — | US | disclosed |
| US-10588854-B2 | Polymer implants for treatment of metabolic disorders | UNIVERSITY OF SOUTH CAROLINA (US) | 2020-03-17 | — | — | US | disclosed |
| US-20190000749-A1 | Polymer Implants for Treatment of Metabolic Disorders | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2019-01-03 | — | — | US | disclosed |
| US-10092508-B2 | Polymer implants for treatment of metabolic disorders | UNIVERSITY OF SOUTH CAROLINA (US) | 2018-10-09 | — | — | US | disclosed |
| US-20170367974-A1 | Polymer Implants For Treatment Of Metabolic Disorders | UNIVERSITY OF SOUTH CAROLINA | 2017-12-28 | — | — | US | disclosed |
| US-9808434-B2 | Compound for treating cancer and diabetes | CITY OF HOPE (US) | 2017-11-07 | — | — | US | disclosed |
| US-9808434-B2 | Compound for treating cancer and diabetes | CITY OF HOPE (US) | 2017-11-07 | — | — | US | disclosed |
| US-20160354327-A1 | COMPOUND FOR TREATING CANCER AND DIABETES | CITY OF HOPE | 2016-12-08 | — | — | US | disclosed |
| US-20160354327-A1 | COMPOUND FOR TREATING CANCER AND DIABETES | CITY OF HOPE | 2016-12-08 | — | — | US | disclosed |
| WO-2012103523-A2 | NOVEL MODULATORS OF DEVELOPMENT OF ADIPOCYTE AND CANCER CELLS | RAHBAR SAMUEL (US) | 2012-08-02 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170367974-A1 | Polymer Implants For Treatment Of Metabolic Disorders | LRBA, FABP4, APMAP | P2RY1 3152/4885EPHX2 4768/4885EPHX1 4477/4885 |
| US-10588854-B2 | Polymer implants for treatment of metabolic disorders | LRBA, FABP4, APMAP | P2RY1 3152/4885EPHX2 4768/4885EPHX1 4477/4885 |
| US-20220023240-A1 | COMPOUND FOR TREATING CANCER AND DIABETES | TP53, VHL, SLC2A4 | P2RY1 4063/4885EPHX2 3211/4885EPHX1 3055/4885 |
| US-11583509-B2 | Compound for treating cancer and diabetes | TP53, VHL, SLC2A4 | P2RY1 4063/4885EPHX2 3211/4885EPHX1 3055/4885 |
| US-10092508-B2 | Polymer implants for treatment of metabolic disorders | LRBA, FABP4, APMAP | P2RY1 3152/4885EPHX2 4768/4885EPHX1 4477/4885 |
| US-20160354327-A1 | COMPOUND FOR TREATING CANCER AND DIABETES | TP53, VHL, SLC2A4 | P2RY1 4063/4885EPHX2 3211/4885EPHX1 3055/4885 |
| US-20190000749-A1 | Polymer Implants for Treatment of Metabolic Disorders | LRBA, FABP4, APMAP | P2RY1 3152/4885EPHX2 4768/4885EPHX1 4477/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.