Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 1/20 | 0.38 |
| ▸ | TDO2 | P48775 | 1/20 | 0.38 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.38 |
| ▸ | LIPG | Q9Y5X9 | 4/20 | 0.38 |
| ▸ | LPL | P06858 | 3/20 | 0.38 |
| ▸ | P4HB | P07237 | 1/20 | 0.37 |
| ▸ | F2 | P00734 | 1/20 | 0.36 |
| ▸ | F11 | P03951 | 1/20 | 0.36 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.36 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.36 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.36 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.36 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.35 |
| ▸ | EGFR | P00533 | 2/20 | 0.35 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.35 |
| ▸ | KDR | P35968 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL482096 | 0.90 | LIPG (0.38) | IDO1TDO2IRAK4LIPGLPL | |
| SCHEMBL15261921 | 0.83 | USP30 (0.43) | IDO1TDO2IRAK4F2F11 | |
| SCHEMBL13028373 | 0.79 | DYRK1A (0.42) | IDO1TDO2IRAK4LIPGLPL | |
| SCHEMBL2144110 | 0.77 | MTNR1A (0.49) | IDO1TDO2IRAK4LIPGROCK1 | |
| SCHEMBL14765095 | 0.76 | HTT (0.52) | LIPGLPL | |
| SCHEMBL3044285 | 0.76 | LPL (0.41) | IDO1TDO2IRAK4LIPGLPL | |
| SCHEMBL18130872 | 0.76 | IRAK4 (0.39) | IDO1TDO2IRAK4LIPGLPL | |
| SCHEMBL15288424 | 0.76 | LPL (0.41) | IDO1TDO2IRAK4LIPGLPL | |
| SCHEMBL19836335 | 0.76 | IRAK4 (0.39) | IDO1TDO2IRAK4LIPGLPL | |
| SCHEMBL23638475 | 0.75 | MTNR1A (0.39) | IDO1TDO2IRAK4LIPGLPL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2670410-A1 | ANTIMICROBIAL 4-OXOQUINOLIZINES | Evolva SA (CH) | 2013-12-11 | — | — | EP | disclosed |
| WO-2012104305-A1 | ANTIMICROBIAL 4-OXOQUINOLIZINES | EVOLVA SA (CH) | 2012-08-09 | — | — | WO | disclosed |