Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR3 | P49019 | 16/20 | 0.48 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.45 |
| ▸ | KCNMA1 | Q12791 | 1/20 | 0.44 |
| ▸ | RXRA | P19793 | 1/20 | 0.43 |
| ▸ | PPARG | P37231 | 1/20 | 0.43 |
| ▸ | NAMPT | P43490 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1249929 | 0.78 | HCAR3 (0.45) | HCAR3HPGDHCAR2KCNMA1RXRA | |
| SCHEMBL5437652 | 0.77 | HCAR3 (0.57) | HCAR3HPGDHCAR2RXRAPPARG | |
| SCHEMBL2490016 | 0.76 | HCAR3 (0.60) | HCAR3HPGDHCAR2RXRAPPARG | |
| SCHEMBL30864289 | 0.74 | HCAR3 (0.57) | HCAR3HPGDHCAR2RXRAPPARG | |
| SCHEMBL15855876 | 0.74 | TSHR (0.61) | — | |
| SCHEMBL23675185 | 0.73 | HCAR3 (0.56) | HCAR3HPGDHCAR2RXRAPPARG | |
| SCHEMBL1965510 | 0.72 | HSD17B10 (0.42) | HPGD | |
| SCHEMBL1250575 | 0.71 | HCAR3 (0.50) | HCAR3HPGDHCAR2RXRAPPARG | |
| SCHEMBL1248894 | 0.71 | HCAR3 (0.50) | HCAR3HPGDHCAR2KCNMA1RXRA | |
| SCHEMBL2361755 | 0.70 | HSD17B10 (0.43) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7879893-B2 | Zinc binding ligand; sustained release of insulin | NOVO NORDISK A/S (DK) | 2011-02-01 | — | — | US | disclosed |