Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | LCK | P06239 | 1/20 | 0.42 |
| ▸ | RORC | P51449 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | CSNK2A2 | P19784 | 2/20 | 0.39 |
| ▸ | CSNK2B | P67870 | 2/20 | 0.39 |
| ▸ | CSNK2A1 | P68400 | 2/20 | 0.39 |
| ▸ | F9 | P00740 | 3/20 | 0.37 |
| ▸ | PLA2G10 | O15496 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | MYC | P01106 | 1/20 | 0.36 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.36 |
| ▸ | EHMT2 | Q96KQ7 | 1/20 | 0.35 |
| ▸ | EHMT1 | Q9H9B1 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1964379 | 0.89 | KIF11 (0.40) | HSD17B10THRBLCKRORCSMN1; SMN2 | |
| SCHEMBL1966409 | 0.86 | LCK (0.42) | HSD17B10THRBLCKRORCSMN1; SMN2 | |
| SCHEMBL1973510 | 0.85 | HSD17B10 (0.44) | HSD17B10THRBLCKRORCSMN1; SMN2 | |
| SCHEMBL1967727 | 0.83 | LCK (0.56) | HSD17B10THRBLCKRORCSMN1; SMN2 | |
| SCHEMBL1970564 | 0.83 | LCK (0.41) | HSD17B10THRBLCKRORCSMN1; SMN2 | |
| SCHEMBL1967636 | 0.82 | LCK (0.46) | HSD17B10THRBLCKRORCSMN1; SMN2 | |
| SCHEMBL1964840 | 0.82 | LCK (0.47) | HSD17B10THRBLCKRORCSMN1; SMN2 | |
| SCHEMBL1964805 | 0.81 | KIF11 (0.41) | HSD17B10LCKRORCCSNK2A2CSNK2B | |
| SCHEMBL1965823 | 0.80 | LCK (0.42) | HSD17B10THRBLCKRORCSMN1; SMN2 | |
| SCHEMBL2361755 | 0.80 | HSD17B10 (0.43) | HSD17B10THRBRORCSMN1; SMN2HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2334652-A1 | 1H-BENZ IMIDAZOLE-5-CARBOXAMIDES AS ANTI-INFLAMMATORY AGENTS | Boehringer Ingelheim International GmbH (DE) | 2011-06-22 | — | — | EP | claimed |