Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.74 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.74 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.74 |
| ▸ | GAA | P10253 | 3/20 | 0.74 |
| ▸ | MEN1 | O00255 | 5/20 | 0.70 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.70 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.70 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.70 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.70 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.70 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.70 |
| ▸ | TSHR | P16473 | 1/20 | 0.70 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.70 |
| ▸ | DRD3 | P35462 | 1/20 | 0.70 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.70 |
| ▸ | APP | P05067 | 7/20 | 0.68 |
| ▸ | CA1 | P00915 | 1/20 | 0.65 |
| ▸ | CA2 | P00918 | 1/20 | 0.65 |
| ▸ | CA9 | Q16790 | 1/20 | 0.65 |
| ▸ | LMNA | P02545 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12756285 | 0.91 | MAPT (0.81) | MAPTKMT2AKDM4EGAAMEN1 | |
| SCHEMBL1260486 | 0.85 | MAPT (1.00) | MAPTKMT2AKDM4EGAAMEN1 | |
| SCHEMBL4338954 | 0.84 | MAPT (0.65) | MAPTKMT2AKDM4EGAAMEN1 | |
| SCHEMBL1854311 | 0.84 | MAPT (0.70) | MAPTKMT2AKDM4EGAAMEN1 | |
| SCHEMBL4338431 | 0.84 | MAPT (0.70) | MAPTKMT2AKDM4EGAAMEN1 | |
| SCHEMBL11858486 | 0.84 | KMT2A (0.70) | MAPTKMT2AKDM4EGAAMEN1 | |
| SCHEMBL4662959 | 0.84 | MAPT (0.70) | MAPTKMT2AKDM4EGAAMEN1 | |
| Hydrochloric Acid SCHEMBL21597225 | 0.83 | MAPT (0.68) | MAPTKMT2AKDM4EGAAMEN1 | |
| SCHEMBL4662941 | 0.83 | MAPT (0.68) | MAPTKMT2AKDM4EGAAMEN1 | |
| Edaravone SCHEMBL4704 | 0.82 | KMT2A (1.00) | MAPTKMT2AKDM4EGAAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 50 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230348694-A1 | SHELF LIFE- AND TRANSPORT STABILIZERS FOR POLYMERIZABLE COMPOUNDS | BASF SE (DE) | 2023-11-02 | — | — | US | disclosed |
| US-20230348694-A1 | SHELF LIFE- AND TRANSPORT STABILIZERS FOR POLYMERIZABLE COMPOUNDS | BASF SE (DE) | 2023-11-02 | — | — | US | disclosed |
| US-20230348694-A1 | SHELF LIFE- AND TRANSPORT STABILIZERS FOR POLYMERIZABLE COMPOUNDS | BASF SE (DE) | 2023-11-02 | — | — | US | disclosed |
| CN-114920753-B | 6-fluoro-dihydropyran [2,3-c ] pyrazole derivative and synthetic method and application thereof | 华南理工大学 | 2023-06-20 | — | — | CN | disclosed |
| CN-114920753-A | 6-fluoro-dihydropyrano [2,3-c ] pyrazole derivative and synthetic method and application thereof | 华南理工大学 | 2022-08-19 | — | — | CN | disclosed |
| EP-3828159-A1 | STORAGE AND TRANSPORT STABILIZERS FOR POLYMERIZABLE COMPOUNDS | BASF SE (DE) | 2021-06-02 | — | — | EP | disclosed |
| EP-3828159-A1 | STORAGE AND TRANSPORT STABILIZERS FOR POLYMERIZABLE COMPOUNDS | BASF SE (DE) | 2021-06-02 | — | — | EP | disclosed |
| US-20210128529-A1 | DRUG CONTAINING PYRAZOLONE DERIVATIVE | NOBELPHARMA CO., LTD. (JP) | 2021-05-06 | — | — | US | disclosed |
| CN-112118839-A | Pyrazolone derivative-containing drug | 耐贝医药株式会社 | 2020-12-22 | — | — | CN | disclosed |
| EP-3666270-A1 | DRUG CONTAINING PYRAZOLONE DERIVATIVE | Nobelpharma Co., Ltd. (JP) | 2020-06-17 | — | — | EP | disclosed |
| US-20030082330-A1 | Squarylium compounds and optical recording medium containing the same | KYOWA HAKKO CHEMICAL CO., LTD. (FORMERLY KYOWA YUKA CO., LTD.) (JP) | 2003-05-01 | — | — | US | disclosed |
| EP-1152001-A9 | SQUARYLIUM COMPOUND AND OPTICAL RECORDING MEDIUM CONTAINING THE SAME | KYOWA HAKKO KOGYO CO., LTD. (JP) | 2002-02-27 | — | — | EP | disclosed |
| EP-1152001-A1 | SQUARYLIUM COMPOUND AND OPTICAL RECORDING MEDIUM CONTAINING THE SAME | KYOWA HAKKO KOGYO CO., LTD. (JP) | 2001-11-07 | — | — | EP | disclosed |
| US-RE35801-E | PYRAZOLONE DERIVATIVES | MITSUBISHI CHEMICAL CORPORATION (JP) | 1998-05-19 | — | — | US | disclosed |
| EP-0208874-B1 | PROPHYLACTIC AND THERAPEUTIC AGENT FOR CIRCULATORY DISORDERS | MITSUBISHI KASEI CORPORATION (JP) | 1993-03-24 | — | — | EP | disclosed |
| EP-0138749-B1 | PROCESS FOR MASS DYEING SYNTHETIC POLYAMIDES | CIBA-GEIGY AG (CH) | 1989-08-23 | — | — | EP | disclosed |
| US-4857542-A | INHIBITOR AGAINST LIPID PEROXIDATION | MITSUBISHI CHEMICAL INDUSTRIES LIMITED (JP) | 1989-08-15 | — | — | US | disclosed |
| EP-0208874-A1 | Prophylactic and therapeutic agent for circulatory disorders | MITSUBISHI KASEI CORPORATION (JP) | 1987-01-21 | — | — | EP | disclosed |
| US-4527994-A | Process for mass-coloring nylon with 1:2 chromium complex azo dye | CIBA-GEIGY CORPORATION (US) | 1985-07-09 | — | — | US | disclosed |
| EP-0138749-A2 | Process for mass dyeing synthetic polyamides | CIBA-GEIGY AG (CH) | 1985-04-24 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210128529-A1 | DRUG CONTAINING PYRAZOLONE DERIVATIVE | CYP11B2, CYP3A5, DPYD | MAPT 4271/4885KMT2A 1306/4885KDM4E 694/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.