Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL875496 | 0.91 | MEN1 (0.35) | MEN1POLBKMT2A | |
| SCHEMBL23395120 | 0.83 | MEN1 (0.35) | MEN1POLBKMT2A | |
| Methacrylic Acid SCHEMBL491387 | 0.80 | BLM (0.39) | — | |
| SCHEMBL23395119 | 0.79 | CES2 (0.40) | MEN1POLBKMT2A | |
| SCHEMBL1326296 | 0.77 | — | — | |
| SCHEMBL4294793 | 0.77 | TSHR (0.44) | MEN1POLBKMT2A | |
| SCHEMBL4401431 | 0.76 | CA12 (0.39) | — | |
| SCHEMBL19116014 | 0.75 | ALDH1A1 (0.41) | MEN1POLBKMT2A | |
| SCHEMBL23693369 | 0.74 | BLM (0.32) | — | |
| SCHEMBL12646242 | 0.74 | BLM (0.48) | MEN1POLBKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7884141-B2 | hydrogel contact lenses formed from esterified aminoalcohol monomers; improved surface wettability, water absorption to silicone hydrogel, and decreased accumulation of protein deposits (lysozyme), and reduced absorption of charged biocides which leads to ocular staining | BAUSCH & LOMB INCORPORATED (US) | 2011-02-08 | — | — | US | disclosed |
| EP-2215501-A1 | BIOMEDICAL DEVICES | Bausch & Lomb Incorporated (US) | 2010-08-11 | — | — | EP | disclosed |
| WO-2009064589-A1 | BIOMEDICAL DEVICES | BAUSCH & LOMB INCORPORATED (US) | 2009-05-22 | — | — | WO | disclosed |
| US-20090122260-A1 | Biomedical Devices | SOLTA MEDICAL, INC. | 2009-05-14 | — | — | US | disclosed |