Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.32 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | ALDH2 | P05091 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3676295 | 0.86 | MAPT (0.33) | CYP1A2CYP2C9HPGDMAPK1HIF1A | |
| SCHEMBL11511611 | 0.83 | CYP1A2 (0.32) | CYP1A2CYP2C9HPGDMAPK1HIF1A | |
| SCHEMBL1251000 | 0.82 | CYP1A2 (0.36) | CYP1A2CYP2C9HPGDMAPK1HIF1A | |
| SCHEMBL2167588 | 0.78 | PLA2G1B (0.33) | PLA2G1BPLA2G2A | |
| SCHEMBL2845490 | 0.77 | SIGMAR1 (0.35) | CYP1A2CYP2C9HPGDMAPK1HIF1A | |
| SCHEMBL17240714 | 0.77 | LMNA (0.37) | HSD17B10PLA2G1BPLA2G2AALDH1A1 | |
| SCHEMBL11837765 | 0.77 | LMNA (0.37) | HSD17B10PLA2G1BPLA2G2AALDH1A1 | |
| SCHEMBL1250788 | 0.76 | MAPT (0.46) | MAPTALDH1A1 | |
| SCHEMBL79152 | 0.75 | MAPT (0.36) | MAPTALDH1A1ALDH2 | |
| SCHEMBL11493585 | 0.75 | ALDH1A1 (0.31) | CYP1A2CYP2C9ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1434755-B1 | A NITROGEN-CONTAINING ORTHO ESTER-BASED SURFACTANT, ITS PREPARATION AND USE | AKZO NOBEL NV (NL) | 2011-02-09 | — | — | EP | disclosed |
| US-7713916-B2 | Orthoester-based surfactants and associated methods | HALLIBURTON ENERGY SERVICES, INC. (US) | 2010-05-11 | — | — | US | disclosed |
| US-7700525-B2 | Orthoester-based surfactants and associated methods | HALLIBURTON ENERGY SERVICES, INC. (US) | 2010-04-20 | — | — | US | disclosed |
| US-20100016184-A1 | Orthoester-Based Surfactants and Associated Methods | HALLIBURTON ENERGY SERVICES, INC. | 2010-01-21 | — | — | US | disclosed |
| US-7288510-B2 | Nitrogen-containing ortho ester-based surfactant, its preparation and use | AKZO NOBEL N.V. (NL) | 2007-10-30 | — | — | US | disclosed |
| US-20070066492-A1 | Orthoester-based surfactants and associated methods | HALLIBURTON ENERGY SERVICES, INC. | 2007-03-22 | — | — | US | disclosed |
| US-20070066493-A1 | Orthoester-based surfactants and associated methods | HALLIBURTON ENERGY SERVICES, INC. | 2007-03-22 | — | — | US | disclosed |
| US-20040198631-A1 | Nitrogen-containing ortho ester-based surfactant, its preparation and use | AKZO NOBEL N.V. (NL) | 2004-10-07 | — | — | US | disclosed |