Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AOC3 | Q16853 | 2/20 | 0.42 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.40 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.37 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.36 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.36 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.36 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.36 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19402469 | 0.83 | AOC3 (0.44) | AOC3SLC6A2SLC6A3SLC6A4KAT2B | |
| SCHEMBL9613800 | 0.82 | AOC3 (0.44) | AOC3SLC6A2SLC6A3SLC6A4KAT2B | |
| SCHEMBL21477341 | 0.80 | ALDH1A1 (0.44) | ALDH1A1OPRM1CHRNB2CHRNB4CHRNA3 | |
| SCHEMBL2277962 | 0.80 | AOC3 (0.42) | AOC3SLC6A2SLC6A3SLC6A4KAT2B | |
| SCHEMBL11989946 | 0.79 | CHRNB2 (0.53) | AOC3ALDH1A1OPRM1CHRNB2CHRNB4 | |
| SCHEMBL6943365 | 0.78 | KAT2B (0.38) | AOC3SLC6A2SLC6A3SLC6A4KAT2B | |
| SCHEMBL17571750 | 0.78 | AOC3 (0.47) | AOC3SLC6A2SLC6A3SLC6A4KAT2B | |
| SCHEMBL31016671 | 0.78 | AOC3 (0.47) | AOC3SLC6A2SLC6A3SLC6A4KAT2B | |
| Hydrochloric Acid SCHEMBL27689197 | 0.78 | CHRNB2 (0.51) | AOC3SLC6A2SLC6A3SLC6A4ALDH1A1 | |
| SCHEMBL11990055 | 0.77 | ALDH1A1 (0.49) | AOC3KAT2BALDH1A1OPRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110178066-A1 | Hydroxypiperidine derivatives and uses thereof | AVALON PHARMACEUTICALS | 2011-07-21 | — | — | US | disclosed |
| US-20100249111-A1 | MULTI-RING COMPOUNDS AND USES THEREOF | AVALON PHARMACEUTICALS (US) | 2010-09-30 | — | — | US | disclosed |
| US-20090036429-A1 | Hydroxypiperidine Derivatives and Uses Thereof | AVALON PHARMACEUTICALS | 2009-02-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100249111-A1 | MULTI-RING COMPOUNDS AND USES THEREOF | TP53, BCOR, HPGDS | AOC3 2044/4885SLC6A2 4733/4885SLC6A3 4490/4885 |
| US-20110178066-A1 | Hydroxypiperidine derivatives and uses thereof | HPGDS, HPGD, DPYD | AOC3 3231/4885SLC6A2 4434/4885SLC6A3 3996/4885 |
| US-20090036429-A1 | Hydroxypiperidine Derivatives and Uses Thereof | HPGDS, HPGD, DPYD | AOC3 3231/4885SLC6A2 4434/4885SLC6A3 3996/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.