Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 2/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | SLC6A11 | P48066 | 4/20 | 0.47 |
| ▸ | SLC6A1 | P30531 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | SLC6A12 | P48065 | 1/20 | 0.42 |
| ▸ | SLC6A13 | Q9NSD5 | 1/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28520814 | 0.89 | HPGD (0.42) | HPGDSMN1; SMN2LMNACYP1A2HTT | |
| SCHEMBL11302489 | 0.89 | HPGD (0.42) | HPGDSMN1; SMN2LMNACYP1A2HTT | |
| SCHEMBL27056605 | 0.85 | MEN1 (0.57) | HPGDSLC6A11SLC6A1KMT2AALDH1A1 | |
| SCHEMBL2567526 | 0.85 | MEN1 (0.57) | HPGDSLC6A11SLC6A1KMT2AALDH1A1 | |
| SCHEMBL2567523 | 0.85 | MEN1 (0.57) | HPGDSLC6A11SLC6A1KMT2AALDH1A1 | |
| SCHEMBL9223044 | 0.85 | MGLL (0.45) | — | |
| SCHEMBL9692839 | 0.83 | SLC6A11 (0.47) | HPGDSMN1; SMN2L3MBTL1SLC6A11SLC6A1 | |
| Hydrochloric Acid SCHEMBL9221696 | 0.82 | MGLL (0.43) | — | |
| SCHEMBL31259093 | 0.82 | KIF11 (0.43) | SLC6A1KMT2AMEN1TDP1 | |
| SCHEMBL22879134 | 0.80 | MEN1 (0.43) | SLC6A11SLC6A1KMT2ALMNAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019185477-A1 | CYCLIC DINUCLEOTIDE COMPOUNDS CONTAINING 2-AZA-HYPOXANTHINE OR 6H-PYTAZOLO[1,5-D][1,2,4]TRIAZIN-7-ONE AS STING AGONISTS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2019-10-03 | — | — | WO | disclosed |
| WO-2011084345-A1 | A METHOD FOR RAPIDLY EVALUATING PERFORMANCE OF SHORT INTERFERING RNA WITH NOVEL CHEMICAL MODIFICATIONS | MERCK SHARP & DOHME CORP. (US) | 2011-07-14 | — | — | WO | disclosed |