Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.62 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.54 |
| ▸ | TP53BP1 | Q12888 | 4/20 | 0.52 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.50 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.50 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.49 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10630944 | 0.93 | ALDH1A1 (0.57) | SMN1; SMN2KDM4EALDH1A1NPSR1HSD17B10 | |
| SCHEMBL6258472 | 0.90 | SMN1; SMN2 (0.79) | SMN1; SMN2KDM4EALDH1A1TP53BP1L3MBTL1 | |
| SCHEMBL9576605 | 0.89 | LMNA (0.62) | SMN1; SMN2KDM4EALDH1A1LMNA | |
| SCHEMBL27033126 | 0.89 | SMN1; SMN2 (0.54) | SMN1; SMN2KDM4EALDH1A1NPSR1HSD17B10 | |
| SCHEMBL24051989 | 0.88 | GRIN1 (0.62) | SMN1; SMN2KDM4EALDH1A1LMNA | |
| SCHEMBL10123874 | 0.88 | TERT (0.55) | SMN1; SMN2KDM4EALDH1A1NPSR1HSD17B10 | |
| SCHEMBL3650167 | 0.88 | HPGD (0.54) | SMN1; SMN2KDM4EALDH1A1NPSR1HSD17B10 | |
| SCHEMBL15923326 | 0.88 | SMN1; SMN2 (0.69) | SMN1; SMN2KDM4EALDH1A1L3MBTL1LMNA | |
| SCHEMBL12497737 | 0.88 | ALDH1A1 (0.64) | SMN1; SMN2KDM4EALDH1A1TDP1 | |
| SCHEMBL9168059 | 0.88 | SMN1; SMN2 (0.69) | SMN1; SMN2KDM4EALDH1A1L3MBTL1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2521747-B1 | NOVEL RESIN CURING AGENTS | HEXCEL COMPOSITES LTD (GB) | 2021-06-16 | — | — | EP | disclosed |
| US-8981033-B2 | Resin curing agents | HEXCEL COMPOSITES LIMITED (GB) | 2015-03-17 | — | — | US | disclosed |
| US-8981033-B2 | Resin curing agents | HEXCEL COMPOSITES LIMITED (GB) | 2015-03-17 | — | — | US | disclosed |
| US-20130217803-A1 | NOVEL RESIN CURING AGENTS | HEXCEL COMPOSITES LIMITED (GB) | 2013-08-22 | — | — | US | disclosed |
| US-20130217803-A1 | NOVEL RESIN CURING AGENTS | HEXCEL COMPOSITES LIMITED (GB) | 2013-08-22 | — | — | US | disclosed |
| WO-2011083329-A2 | NOVEL RESIN CURING AGENTS | HEXCEL COMPOSITES LIMITED (GB) | 2011-07-14 | — | — | WO | disclosed |