Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP12 | P39900 | 3/20 | 0.48 |
| ▸ | MMP13 | P45452 | 2/20 | 0.48 |
| ▸ | AR | P10275 | 1/20 | 0.40 |
| ▸ | LTA4H | P09960 | 1/20 | 0.38 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.37 |
| ▸ | SLC18A2 | Q05940 | 1/20 | 0.35 |
| ▸ | MMP2 | P08253 | 1/20 | 0.34 |
| ▸ | MMP9 | P14780 | 1/20 | 0.34 |
| ▸ | MMP14 | P50281 | 1/20 | 0.34 |
| ▸ | STAT3 | P40763 | 1/20 | 0.34 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.34 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.34 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.34 |
| ▸ | ACACB | O00763 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12517335 | 0.93 | MMP12 (0.53) | MMP12MMP13LTA4HFFAR1MMP2 | |
| SCHEMBL12517696 | 0.80 | MMP12 (0.39) | MMP12MMP13ARMMP2MMP9 | |
| SCHEMBL10928948 | 0.79 | HTT (0.50) | STAT3ADRB2ADRB1ADRB3 | |
| SCHEMBL11451860 | 0.77 | SLC18A2 (0.52) | SLC18A2STAT3ADRB2ADRB1ADRB3 | |
| SCHEMBL11075117 | 0.77 | ACACB (0.47) | MMP12ARLTA4HADRB2ADRB1 | |
| SCHEMBL11100113 | 0.75 | PPARA (0.40) | MMP12MMP13ARMMP2MMP9 | |
| SCHEMBL12516488 | 0.75 | MMP12 (0.36) | MMP12MMP13MMP2MMP9MMP14 | |
| SCHEMBL14696198 | 0.75 | AR (0.78) | ARADRB2ADRB1ADRB3 | |
| SCHEMBL14696201 | 0.75 | AR (0.78) | ARADRB2ADRB1ADRB3 | |
| SCHEMBL409924 | 0.74 | TAAR1 (0.45) | MMP12MMP13MMP2MMP9MMP14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011082488-A1 | BISPHENOL DERIVATIVE THERAPEUTICS AND METHODS FOR THEIR USE | BRITISH COLUMBIA CANCER AGENCY BRANCH (CA) | 2011-07-14 | — | — | WO | disclosed |