Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP12 | P39900 | 3/20 | 0.36 |
| ▸ | MMP13 | P45452 | 3/20 | 0.36 |
| ▸ | PPARG | P37231 | 1/20 | 0.33 |
| ▸ | PPARD | Q03181 | 1/20 | 0.33 |
| ▸ | PPARA | Q07869 | 1/20 | 0.33 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.32 |
| ▸ | SPHK2 | Q9NRA0 | 7/20 | 0.32 |
| ▸ | SPHK1 | Q9NYA1 | 7/20 | 0.32 |
| ▸ | S1PR2 | O95136 | 2/20 | 0.32 |
| ▸ | S1PR4 | O95977 | 2/20 | 0.32 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.32 |
| ▸ | S1PR3 | Q99500 | 2/20 | 0.32 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.32 |
| ▸ | MMP2 | P08253 | 1/20 | 0.31 |
| ▸ | MMP9 | P14780 | 1/20 | 0.31 |
| ▸ | MMP14 | P50281 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12517696 | 0.94 | MMP12 (0.39) | MMP12MMP13MMP2MMP9MMP14 | |
| SCHEMBL12516480 | 0.77 | MMP12 (0.31) | MMP12MMP13 | |
| SCHEMBL12516486 | 0.75 | MMP12 (0.48) | MMP12MMP13MMP2MMP9MMP14 | |
| SCHEMBL12516479 | 0.74 | HPGD (0.38) | MMP12MMP13S1PR1 | |
| SCHEMBL3027269 | 0.71 | MMP12 (0.38) | MMP12MMP13PPARGPPARDPPARA | |
| SCHEMBL16299510 | 0.71 | SPHK2 (0.47) | TRPA1SPHK2SPHK1TRPV1 | |
| SCHEMBL11549188 | 0.70 | TRPA1 (0.51) | TRPA1TRPV1 | |
| SCHEMBL409924 | 0.70 | TAAR1 (0.45) | MMP12MMP13PPARGPPARAMMP2 | |
| SCHEMBL16314688 | 0.70 | TAAR1 (0.45) | MMP12MMP13PPARGPPARAMMP2 | |
| SCHEMBL11462575 | 0.70 | TAAR1 (0.45) | MMP12MMP13PPARGPPARAMMP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011082488-A1 | BISPHENOL DERIVATIVE THERAPEUTICS AND METHODS FOR THEIR USE | BRITISH COLUMBIA CANCER AGENCY BRANCH (CA) | 2011-07-14 | — | — | WO | disclosed |