Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 8/20 | 0.41 |
| ▸ | HTT | P42858 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | BCHE | P06276 | 1/20 | 0.38 |
| ▸ | ACHE | P22303 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | PGR | P06401 | 1/20 | 0.37 |
| ▸ | RORA | P35398 | 1/20 | 0.37 |
| ▸ | RORC | P51449 | 1/20 | 0.37 |
| ▸ | RORB | Q92753 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 4/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.35 |
| ▸ | HPGD | P15428 | 3/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.35 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL680118 | 0.94 | ALDH1A1 (0.40) | MAPTHTTLMNABCHEACHE | |
| SCHEMBL18858857 | 0.90 | ALDH1A1 (0.38) | MAPTHTTLMNABCHEACHE | |
| SCHEMBL31151770 | 0.85 | KDM4E (0.46) | MAPTHTTLMNAALDH1A1TSHR | |
| SCHEMBL7139964 | 0.85 | KDM4E (0.46) | MAPTHTTLMNAALDH1A1TSHR | |
| SCHEMBL680762 | 0.83 | ALDH1A1 (0.40) | MAPTHTTLMNAALDH1A1TSHR | |
| SCHEMBL13957096 | 0.82 | MAPT (0.40) | MAPTHTTLMNABCHEACHE | |
| SCHEMBL22721368 | 0.81 | TSPO (0.40) | MAPTHTTACHEALDH1A1MEN1 | |
| SCHEMBL15965732 | 0.80 | KDM4E (0.34) | MAPTHTTALDH1A1MEN1KMT2A | |
| SCHEMBL10042912 | 0.80 | TSPO (0.36) | MAPTHTTALDH1A1MEN1KMT2A | |
| SCHEMBL680511 | 0.78 | BCHE (0.38) | MAPTHTTLMNABCHEACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1932866-B1 | Blends comprising conjugated carbazole polymers, synthesis and usage thereof | MERCK PATENT GMBH (DE) | 2011-07-13 | — | — | EP | disclosed |