Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.40 |
| ▸ | MAPT | P10636 | 5/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | DHFR | P00374 | 1/20 | 0.37 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 5/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.35 |
| ▸ | BCHE | P06276 | 1/20 | 0.35 |
| ▸ | ACHE | P22303 | 1/20 | 0.35 |
| ▸ | AHR | P35869 | 2/20 | 0.34 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.34 |
| ▸ | PGR | P06401 | 1/20 | 0.34 |
| ▸ | RORA | P35398 | 1/20 | 0.34 |
| ▸ | RORC | P51449 | 1/20 | 0.34 |
| ▸ | RORB | Q92753 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18858857 | 0.97 | ALDH1A1 (0.38) | ALDH1A1MAPTTSHRDHFRFGFR1 | |
| SCHEMBL12522701 | 0.94 | MAPT (0.41) | ALDH1A1MAPTTSHRDHFRFGFR1 | |
| SCHEMBL680762 | 0.86 | ALDH1A1 (0.40) | ALDH1A1MAPTTSHRDHFRFGFR1 | |
| SCHEMBL844887 | 0.79 | HTR1D (0.37) | ALDH1A1MAPTFGFR1KDM4EHTT | |
| SCHEMBL2361948 | 0.76 | HTR6 (0.53) | BCHEACHE | |
| SCHEMBL31151770 | 0.75 | KDM4E (0.46) | ALDH1A1MAPTTSHRKDM4EHTT | |
| SCHEMBL7139964 | 0.75 | KDM4E (0.46) | ALDH1A1MAPTTSHRKDM4EHTT | |
| SCHEMBL13957096 | 0.74 | MAPT (0.40) | ALDH1A1MAPTKDM4EHTTMEN1 | |
| SCHEMBL22721368 | 0.73 | TSPO (0.40) | ALDH1A1MAPTKDM4EHTTMEN1 | |
| SCHEMBL17051400 | 0.73 | MAPT (0.35) | MAPTKDM4EHTTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8053547-B2 | Conjugated polymers and blends containing carbazole, representation and use thereof | MERCK PATENT GMBH (DE) | 2011-11-08 | — | — | US | disclosed |
| US-20110068304-A1 | Conjugated Polymers and Blends Containing Carbazole, Representation and Use Thereof | MERCK PATENT GMBH (DE) | 2011-03-24 | — | — | US | disclosed |
| US-7834136-B2 | Conjugated polymers and blends containing carbazole, representation and use thereof | COVION ORGANIC SEMICONDUCTORS GMBH (DE) | 2010-11-16 | — | — | US | disclosed |
| EP-1932866-A1 | Blends comprising conjugated carbazole polymers, synthesis and usage thereof | MERCK PATENT GmbH (DE) | 2008-06-18 | — | — | EP | disclosed |