Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 7/20 | 0.57 |
| ▸ | MEN1 | O00255 | 3/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.52 |
| ▸ | NPC1 | O15118 | 2/20 | 0.52 |
| ▸ | RAB9A | P51151 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.49 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.49 |
| ▸ | DRD3 | P35462 | 4/20 | 0.47 |
| ▸ | SMYD3 | Q9H7B4 | 3/20 | 0.47 |
| ▸ | CRHR1 | P34998 | 1/20 | 0.46 |
| ▸ | HTR2A | P28223 | 2/20 | 0.46 |
| ▸ | HTR1A | P08908 | 1/20 | 0.45 |
| ▸ | DRD4 | P21917 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13181085 | 0.89 | MEN1 (0.58) | DRD2MEN1KMT2ANPC1RAB9A | |
| SCHEMBL7936347 | 0.85 | DRD2 (0.50) | DRD2MEN1KMT2ANPC1RAB9A | |
| SCHEMBL25970123 | 0.83 | ACHE (0.61) | DRD2MEN1KMT2ANPC1RAB9A | |
| SCHEMBL15014137 | 0.83 | MEN1 (0.61) | DRD2MEN1KMT2ANPC1RAB9A | |
| SCHEMBL15014140 | 0.83 | MEN1 (0.61) | DRD2MEN1KMT2ANPC1RAB9A | |
| SCHEMBL18387872 | 0.83 | MEN1 (0.61) | DRD2MEN1KMT2ANPC1RAB9A | |
| SCHEMBL18383343 | 0.80 | MEN1 (0.58) | DRD2MEN1KMT2ANPC1RAB9A | |
| SCHEMBL13152810 | 0.80 | MEN1 (0.58) | DRD2MEN1KMT2ANPC1RAB9A | |
| SCHEMBL13152790 | 0.80 | MEN1 (0.58) | DRD2MEN1KMT2ANPC1RAB9A | |
| SCHEMBL18387839 | 0.79 | MEN1 (0.50) | DRD2MEN1KMT2ANPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012121919-A2 | SELECTIVE LIGANDS FOR THE DOPAMINE 3 (D3) RECEPTOR AND METHODS OF USING THE SAME | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (US) | 2012-09-13 | — | — | WO | disclosed |