Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.46 |
| ▸ | TTK | P33981 | 3/20 | 0.45 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.44 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.44 |
| ▸ | HPGDS | O60760 | 1/20 | 0.44 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.43 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.43 |
| ▸ | CYP46A1 | Q9Y6A2 | 1/20 | 0.43 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.43 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12523886 | 0.85 | DRD2 (0.57) | DRD2MEN1NPC1RAB9AKMT2A | |
| SCHEMBL14082199 | 0.84 | MEN1 (0.65) | MEN1NPC1RAB9AKMT2ASMN1; SMN2 | |
| SCHEMBL14082175 | 0.80 | TRPV1 (0.54) | DRD2MEN1NPC1RAB9AKMT2A | |
| SCHEMBL14082198 | 0.79 | GRM5 (0.58) | MEN1NPC1RAB9AKMT2ASMN1; SMN2 | |
| SCHEMBL14082162 | 0.78 | GRM5 (0.57) | MEN1NPC1RAB9AKMT2ASMN1; SMN2 | |
| SCHEMBL21477359 | 0.77 | TRPV1 (0.53) | MEN1NPC1RAB9AKMT2ASMN1; SMN2 | |
| SCHEMBL14082232 | 0.77 | ATR (0.58) | MEN1NPC1RAB9AKMT2ASMN1; SMN2 | |
| SCHEMBL14082178 | 0.76 | HPGDS (0.61) | DRD2MEN1NPC1RAB9AKMT2A | |
| SCHEMBL13181085 | 0.75 | MEN1 (0.58) | DRD2MEN1NPC1RAB9AKMT2A | |
| SCHEMBL228988 | 0.74 | DRD2 (0.58) | DRD2HPGDS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010025235-A1 | SELECTIVE LIGANDS FOR THE DOPAMINE 3 (D3) RECEPTOR AND METHODS OF USING THE SAME | REGENTS OF THE UNIVERSITY OF MICHIGAN (US) | 2010-03-04 | — | — | WO | disclosed |