Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 8/20 | 0.46 |
| ▸ | MME | P08473 | 6/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17771398 | 0.78 | ACE (0.55) | ACEMME | |
| SCHEMBL12525644 | 0.73 | ACE (0.52) | ACEMME | |
| SCHEMBL12528549 | 0.72 | ACE (0.49) | ACEMME | |
| SCHEMBL12527637 | 0.71 | ACE (0.49) | ACEMME | |
| SCHEMBL12526768 | 0.71 | ACE (0.42) | ACEMME | |
| SCHEMBL12495059 | 0.70 | MME (0.48) | ACEMME | |
| SCHEMBL12526745 | 0.70 | MME (0.48) | ACEMME | |
| SCHEMBL7246639 | 0.70 | FPR2 (0.43) | — | |
| SCHEMBL12494708 | 0.69 | ACE (0.78) | ACEMME | |
| SCHEMBL12526776 | 0.69 | ACE (0.78) | ACEMME |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9346852-B2 | Substituted adipic acid amides and uses thereof | BRISTOL-MYERS SCUIBB COMPANY (US) | 2016-05-24 | — | — | US | disclosed |
| WO-2012125622-A1 | SUBSTITUTED ADIPIC ACID AMIDES AND USES THEREOF | BRISTOL-MYERS SQUIBB COMPANY (US) | 2012-09-20 | — | — | WO | disclosed |