Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR4A2 | P43354 | 1/20 | 0.39 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.36 |
| ▸ | PDCD1 | Q15116 | 2/20 | 0.33 |
| ▸ | CD274 | Q9NZQ7 | 2/20 | 0.33 |
| ▸ | AOC3 | Q16853 | 4/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.32 |
| ▸ | ALOX5AP | P20292 | 2/20 | 0.32 |
| ▸ | FEN1 | P39748 | 2/20 | 0.32 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.31 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.31 |
| ▸ | CNR2 | P34972 | 1/20 | 0.30 |
| ▸ | JAK2 | O60674 | 1/20 | 0.30 |
| ▸ | TYK2 | P29597 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15000542 | 0.86 | NR4A2 (0.35) | NR4A2LRRK2PDCD1CD274AOC3 | |
| SCHEMBL12526579 | 0.83 | KCNH2 (0.42) | NR4A2LRRK2PDCD1CD274AOC3 | |
| SCHEMBL15000467 | 0.81 | NR4A2 (0.35) | NR4A2LRRK2PDCD1CD274AOC3 | |
| SCHEMBL12526552 | 0.80 | MYC (0.35) | NR4A2LRRK2AOC3HIF1APTGDR2 | |
| SCHEMBL12526321 | 0.78 | NR4A2 (0.48) | NR4A2LRRK2PDCD1CD274AOC3 | |
| SCHEMBL12526543 | 0.77 | DGAT1 (0.41) | NR4A2LRRK2PDCD1CD274AOC3 | |
| SCHEMBL12525403 | 0.74 | SCN9A (0.42) | NR4A2LRRK2PDCD1CD274AOC3 | |
| SCHEMBL28210685 | 0.74 | NR4A2 (0.44) | NR4A2LRRK2PDCD1CD274ALOX5AP | |
| SCHEMBL12525396 | 0.73 | AOC3 (0.40) | NR4A2LRRK2PDCD1CD274AOC3 | |
| SCHEMBL9548114 | 0.71 | PDCD1 (0.60) | NR4A2PDCD1CD274KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012124696-A1 | GUANIDINE COMPOUND | アステラス製薬株式会社 (JP) | 2012-09-20 | — | — | WO | disclosed |