Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KLKB1 | P03952 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 6/20 | 0.39 |
| ▸ | MAPT | P10636 | 5/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | POLB | P06746 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.39 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | RECQL | P46063 | 2/20 | 0.36 |
| ▸ | STAT3 | P40763 | 2/20 | 0.36 |
| ▸ | NSD2 | O96028 | 1/20 | 0.35 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.35 |
| ▸ | CA12 | O43570 | 1/20 | 0.35 |
| ▸ | CA9 | Q16790 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17145346 | 0.91 | KLKB1 (0.46) | KLKB1GAAMAPTKDM4EMEN1 | |
| SCHEMBL12526832 | 0.84 | KLKB1 (0.41) | KLKB1GAAMAPTKDM4EMEN1 | |
| SCHEMBL12526833 | 0.82 | KDM4E (0.39) | GAAMAPTKDM4EMEN1POLB | |
| SCHEMBL18123831 | 0.81 | KDM4E (0.38) | GAAMAPTKDM4EMEN1POLB | |
| SCHEMBL20089233 | 0.81 | LMNA (0.37) | KLKB1GAAMAPTKDM4EMEN1 | |
| SCHEMBL18123699 | 0.81 | MAPT (0.37) | GAAMAPTKDM4EMEN1POLB | |
| Hydrochloric Acid SCHEMBL29879996 | 0.80 | LMNA (0.36) | KLKB1GAAMAPTKDM4EMEN1 | |
| SCHEMBL12525445 | 0.80 | PDE4A (0.38) | KLKB1GAAMAPTKDM4EMEN1 | |
| SCHEMBL14656256 | 0.79 | KDM4E (0.50) | GAAMAPTKDM4EMEN1POLB | |
| SCHEMBL15200611 | 0.79 | ALOX15 (0.41) | GAAMAPTKDM4EMEN1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012119265-A1 | NOVEL ESTERS OF 4,9-DIHYDROXY-NAPHTHO[2,3-b]FURANS FOR DISEASE THERAPIES | ZHOUSHAN HAIZHONGZHOU XINSHENG PHARMACEUTICALS CO., LTD. (CN) | 2012-09-13 | — | — | WO | disclosed |