Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR5 | P51681 | 20/20 | 0.68 |
| ▸ | CHRM2 | P08172 | 14/20 | 0.68 |
| ▸ | CHRM1 | P11229 | 4/20 | 0.65 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.65 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12542219 | 0.90 | CCR5 (0.81) | CCR5CHRM2CHRM1CHRM3 | |
| SCHEMBL12531292 | 0.88 | CCR5 (0.86) | CCR5CHRM2CHRM1CHRM3 | |
| SCHEMBL410793 | 0.86 | CCR5 (0.83) | CCR5CHRM2CHRM1CHRM3 | |
| SCHEMBL12531415 | 0.84 | CCR5 (0.74) | CCR5CHRM2CHRM1CHRM3 | |
| SCHEMBL16503427 | 0.83 | CCR5 (0.84) | CCR5CHRM2CHRM1CHRM3 | |
| SCHEMBL18541410 | 0.82 | CCR5 (0.73) | CCR5CHRM2CHRM1CHRM3 | |
| SCHEMBL12420339 | 0.82 | CCR5 (0.73) | CCR5CHRM2CHRM1CHRM3 | |
| SCHEMBL5076337 | 0.79 | CCR5 (1.00) | CCR5CHRM2CHRM1CHRM3 | |
| SCHEMBL14529305 | 0.79 | CCR5 (1.00) | CCR5CHRM2CHRM1CHRM3 | |
| SCHEMBL5076339 | 0.79 | CCR5 (1.00) | CCR5CHRM2CHRM1CHRM3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130129625-A1 | IN VIVO IMAGING AGENTS | HAMMERSMITH IMANET LIMITED (GB) | 2013-05-23 | — | — | US | disclosed |
| US-20130129626-A1 | IN VIVO IMAGING AGENTS | HAMMERSMITH IMANET LIMITED (GB) | 2013-05-23 | — | — | US | disclosed |
| US-20110129419-A1 | IN VIVO IMAGING AGENTS | GE HEALTHCARE LIMITED (GB) | 2011-06-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110129419-A1 | IN VIVO IMAGING AGENTS | CCR5, CCR2, CX3CR1 | CCR5 1/4885CHRM2 1260/4885CHRM1 1805/4885 |
| US-20130129625-A1 | IN VIVO IMAGING AGENTS | CCR5, CCR2, CX3CR1 | CCR5 1/4885CHRM2 1260/4885CHRM1 1805/4885 |
| US-20130129626-A1 | IN VIVO IMAGING AGENTS | CCR5, CCR2, CX3CR1 | CCR5 1/4885CHRM2 1260/4885CHRM1 1805/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.