SCHEMBL1253192

SCHEMBL1253192

Cc1ccc(C(CCC(=O)O)(C(=O)O)c2ccc(C)cc2)cc1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.47
ESR1 P03372 1/20 0.47
CYP3A4 P08684 1/20 0.47
ESR2 Q92731 1/20 0.47
KMT2A Q03164 4/20 0.47
RAB9A P51151 2/20 0.45
L3MBTL1 Q9Y468 1/20 0.44
FFAR1 O14842 2/20 0.41
CHEK1 O14757 1/20 0.41
FYN P06241 1/20 0.41
PDGFRB P09619 1/20 0.41
PIM1 P11309 1/20 0.41
FGFR1 P11362 1/20 0.41
FLT1 P17948 1/20 0.41
GRK5 P34947 1/20 0.41
MAP2K2 P36507 1/20 0.41
MAPK8 P45983 1/20 0.41
CDK8 P49336 1/20 0.41
RPS6KA3 P51812 1/20 0.41
PRKX P51817 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9562152 0.83 ESR1 (0.62) ALDH1A1ESR1CYP3A4ESR2RAB9A
SCHEMBL379350 0.82 CYP2C19 (0.44) ALDH1A1ESR1CYP3A4ESR2FFAR1
SCHEMBL4016674 0.81 CHEK1 (0.44) ALDH1A1ESR1CYP3A4ESR2KMT2A
SCHEMBL2220563 0.81 CYP2C19 (0.42) ALDH1A1KMT2ARAB9AL3MBTL1KIF11
SCHEMBL28271027 0.81 NPC1 (0.49) ALDH1A1ESR1CYP3A4ESR2RAB9A
SCHEMBL5936700 0.79 ALDH1A1 (0.73) ALDH1A1ESR1CYP3A4ESR2KMT2A
SCHEMBL6998994 0.79 ALDH1A1 (0.53) ALDH1A1ESR1CYP3A4ESR2KMT2A
SCHEMBL10599087 0.79 HTT (0.50) ALDH1A1ESR1CYP3A4ESR2KMT2A
SCHEMBL1916607 0.79 ALDH1A1 (0.41) ALDH1A1ESR1CYP3A4ESR2KMT2A
SCHEMBL28305527 0.76 CYP2C19 (0.52) ALDH1A1KMT2ARAB9AKIF11NPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8158218-B2 Process for producing optical film, optical film, polarizer, and liquid crystal display KONICA MINOLTA OPTO, INC. (JP) 2012-04-17 US disclosed
US-20110033640-A1 PROCESS FOR PRODUCING OPTICAL FILM, OPTICAL FILM, POLARIZER, AND LIQUID CRYSTAL DISPLAY KONICA MINOLTA OPTO, INC. (JP) 2011-02-10 US disclosed