Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNB2 | P17787 | 3/20 | 0.51 |
| ▸ | CHRNA4 | P43681 | 3/20 | 0.51 |
| ▸ | CHRNA7 | P36544 | 2/20 | 0.51 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.48 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | CHRM5 | P08912 | 3/20 | 0.41 |
| ▸ | CHRM3 | P20309 | 3/20 | 0.41 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.41 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.41 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.41 |
| ▸ | KDM1A | O60341 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25997962 | 0.88 | SLC18A3 (0.57) | CHRNB2CHRNA4CHRNA7SLC18A3SIGMAR1 | |
| SCHEMBL6268948 | 0.88 | SLC18A3 (0.57) | CHRNB2CHRNA4CHRNA7SLC18A3SIGMAR1 | |
| SCHEMBL170704 | 0.88 | CHRNB2 (0.63) | CHRNB2CHRNA4CHRNA7MEN1CYP2D6 | |
| SCHEMBL21232 | 0.88 | CHRNB2 (0.63) | CHRNB2CHRNA4CHRNA7MEN1CYP2D6 | |
| SCHEMBL167264 | 0.88 | CHRNB2 (0.63) | CHRNB2CHRNA4CHRNA7MEN1CYP2D6 | |
| Hydrochloric Acid SCHEMBL28196337 | 0.86 | CHRNB2 (0.50) | CHRNB2CHRNA4CHRNA7SLC18A3SIGMAR1 | |
| Hydrochloric Acid SCHEMBL12497423 | 0.86 | CHRNB2 (0.61) | CHRNB2CHRNA4CHRNA7MEN1CYP2D6 | |
| Hydrochloric Acid SCHEMBL841177 | 0.86 | CHRNB2 (0.61) | CHRNB2CHRNA4CHRNA7MEN1CYP2D6 | |
| Ammonia Solution, Strong SCHEMBL3517185 | 0.86 | CHRNB2 (0.61) | CHRNB2CHRNA4CHRNA7MEN1CYP2D6 | |
| Hydrochloric Acid SCHEMBL27952288 | 0.86 | CHRNB2 (0.61) | CHRNB2CHRNA4CHRNA7MEN1CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110136814-A1 | Diazepine and Diazocane Compounds As MC4 Agonists | ANDREWS MARK DAVID | 2011-06-09 | — | — | US | disclosed |
| US-20110136814-A1 | Diazepine and Diazocane Compounds As MC4 Agonists | ANDREWS MARK DAVID | 2011-06-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110136814-A1 | Diazepine and Diazocane Compounds As MC4 Agonists | MC4R, CHRM4, GPR4 | CHRNB2 77/4885CHRNA4 4/4885CHRNA7 36/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.