Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.39 |
| ▸ | THPO | P40225 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | BLM | P54132 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.35 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.35 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.35 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.33 |
| ▸ | FOLH1 | Q04609 | 4/20 | 0.33 |
| ▸ | NAALAD2 | Q9Y3Q0 | 2/20 | 0.32 |
| ▸ | RIMKLA | Q8IXN7 | 1/20 | 0.31 |
| ▸ | GNPAT | O15228 | 1/20 | 0.31 |
| ▸ | PAM | P19021 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10308608 | 1.00 | ALDH1A1 (0.42) | ALDH1A1MAPTKDM4ETHRBALOX15 | |
| SCHEMBL23685458 | 0.86 | ALDH1A1 (0.41) | ALDH1A1MAPTKDM4ETHRBALOX15 | |
| SCHEMBL10308346 | 0.86 | ALDH1A1 (0.41) | ALDH1A1MAPTKDM4ETHRBALOX15 | |
| SCHEMBL12537168 | 0.85 | DPP4 (0.40) | ALDH1A1MAPTKDM4ETHRBALOX15 | |
| SCHEMBL22929119 | 0.82 | NAALAD2 (0.32) | ALDH1A1NAALAD2 | |
| SCHEMBL19477961 | 0.82 | ALDH1A1 (0.36) | ALDH1A1FOLH1 | |
| SCHEMBL22301081 | 0.82 | ALDH1A1 (0.36) | ALDH1A1FOLH1 | |
| SCHEMBL12537183 | 0.82 | ALDH1A1 (0.44) | ALDH1A1MAPTKDM4ETHRBALOX15 | |
| SCHEMBL24983988 | 0.81 | MAPT (0.43) | ALDH1A1MAPTKDM4ETHRBALOX15 | |
| SCHEMBL8254919 | 0.81 | MAPT (0.43) | ALDH1A1MAPTKDM4ETHRBALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110130349-A1 | Compounds and Methods for Treating Toll-Like Receptor 2-Related Diseases and Conditions | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2011-06-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110130349-A1 | Compounds and Methods for Treating Toll-Like Receptor 2-Related Diseases and Conditions | TLR2, TLR6, TLR3 | ALDH1A1 1679/4885MAPT 2253/4885KDM4E 4404/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.