Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.43 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.43 |
| ▸ | THPO | P40225 | 1/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | BLM | P54132 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.38 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.38 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.38 |
| ▸ | FOLH1 | Q04609 | 4/20 | 0.34 |
| ▸ | RIMKLA | Q8IXN7 | 1/20 | 0.34 |
| ▸ | NAALAD2 | Q9Y3Q0 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | SLC15A2 | Q16348 | 1/20 | 0.33 |
| ▸ | GNPAT | O15228 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24983988 | 1.00 | MAPT (0.43) | MAPTKDM4ETHRBALOX15NFKB1 | |
| SCHEMBL14557465 | 0.84 | FOLH1 (0.52) | MAPTKDM4ETHRBALOX15NFKB1 | |
| SCHEMBL14557466 | 0.84 | MAPT (0.57) | MAPTKDM4ETHRBALOX15NFKB1 | |
| SCHEMBL11885251 | 0.84 | MAPT (0.57) | MAPTKDM4ETHRBALOX15NFKB1 | |
| SCHEMBL17718255 | 0.84 | FOLH1 (0.52) | MAPTKDM4ETHRBALOX15NFKB1 | |
| SCHEMBL12661034 | 0.83 | CHRM2 (0.42) | MAPTKDM4ETHRBALOX15NFKB1 | |
| SCHEMBL18133384 | 0.83 | CHRM2 (0.42) | MAPTKDM4ETHRBALOX15NFKB1 | |
| SCHEMBL23446568 | 0.83 | ALDH1A1 (0.42) | ALDH1A1FOLH1RIMKLANAALAD2LMNA | |
| SCHEMBL24967258 | 0.83 | MAPT (0.45) | MAPTKDM4ETHRBALOX15NFKB1 | |
| SCHEMBL27252316 | 0.83 | MAPT (0.41) | MAPTKDM4ETHRBALOX15NFKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240207429-A1 | LINKERS, DRUG LINKERS AND CONJUGATES THEREOF AND METHODS OF USING THE SAME | WILMINGTON TRUST, NATIONAL ASSOCIATION | 2024-06-27 | — | — | US | disclosed |
| WO-2024112809-A2 | CELL-PENETRATING PEPTIDES, CONJUGATES THEREOF, AND METHODS OF THEIR USE | PEPGEN INC. (US) | 2024-05-30 | — | — | WO | disclosed |
| WO-2022192749-A2 | METHODS OF TREATING DUCHENNE MUSCULAR DYSTROPHY USING PEPTIDE-OLIGONUCLEOTIDE CONJUGATES | PEPGEN INC. (US) | 2022-09-15 | — | — | WO | disclosed |
| US-20220125934-A1 | LINKERS | UNITED KINGDOM RESEARCH AND INNOVATION (GB) | 2022-04-28 | — | — | US | disclosed |
| WO-2021104120-A1 | POLYETHYLENE GLYCOL CONJUGATE MEDICAMENT, PREPARATION METHOD THERFOR AND USE THEREOF | 重庆阿普格雷生物科技有限公司 | 2021-06-03 | — | — | WO | disclosed |
| US-9278143-B2 | Imaging agents, process for the preparation thereof and pharmaceutical compositions containing same | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) (FR) | 2016-03-08 | — | — | US | disclosed |
| US-9278143-B2 | Imaging agents, process for the preparation thereof and pharmaceutical compositions containing same | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) (FR) | 2016-03-08 | — | — | US | disclosed |
| US-20140241989-A1 | NOVEL IMAGING AGENTS, PROCESS FOR THE PREPARATION THEREOF AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) (FR) | 2014-08-28 | — | — | US | disclosed |
| US-20140241989-A1 | NOVEL IMAGING AGENTS, PROCESS FOR THE PREPARATION THEREOF AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) (FR) | 2014-08-28 | — | — | US | disclosed |
| US-20120202756-A1 | USE OF PRODRUGS TO AVOID GI MEDIATED ADVERSE EVENTS | FRANKLIN RICHARD (GB) | 2012-08-09 | — | — | US | disclosed |
| US-20120184532-A1 | GALANTAMINE AMINO ACID AND PEPTIDE PRODRUGS AND USES THEREOF | SHIRE LLC (US) | 2012-07-19 | — | — | US | disclosed |
| US-7964640-B2 | Oligomers of straight-chain and unbranched fatty acids and drugs containing these | PLT PATENT & LICENSE TRADING LTD. (GB) | 2011-06-21 | — | — | US | disclosed |
| US-7964640-B2 | Oligomers of straight-chain and unbranched fatty acids and drugs containing these | PLT PATENT & LICENSE TRADING LTD. (GB) | 2011-06-21 | — | — | US | disclosed |
| WO-2011033296-A1 | PRODRUGS OF GUANFACINE | SHIRE LLC (US) | 2011-03-24 | — | — | WO | disclosed |
| US-20110065796-A1 | PRODRUGS OF GUANFACINE | SHIRE LLC (US) | 2011-03-17 | — | — | US | disclosed |
| US-20100286186-A1 | NOVEL DICARBOXYLIC ACID LINKED AMINO ACID AND PEPTIDE PRODRUGS OF OPIOIDS AND USES THEREOF | SHIRE LLC (US) | 2010-11-11 | — | — | US | disclosed |
| US-20090012166-A1 | Oligomers of Straight-Chain and Unbranched Fatty Acids and Drugs Containing These | PLT PATENT & LICENSE TRADING S.L. (ES) | 2009-01-08 | — | — | US | disclosed |
| US-20090012166-A1 | Oligomers of Straight-Chain and Unbranched Fatty Acids and Drugs Containing These | PLT PATENT & LICENSE TRADING S.L. (ES) | 2009-01-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100286186-A1 | NOVEL DICARBOXYLIC ACID LINKED AMINO ACID AND PEPTIDE PRODRUGS OF OPIOIDS AND USES THEREOF | VIP, OPRL1, OPRK1 | MAPT 1430/4885KDM4E 1873/4885THRB 797/4885 |
| US-20090012166-A1 | Oligomers of Straight-Chain and Unbranched Fatty Acids and Drugs Containing These | FASN, FFAR3, FFAR2 | MAPT 337/4885KDM4E 4720/4885THRB 934/4885 |
| US-20220125934-A1 | LINKERS | GABRA5, GABRA2, GABRG2 | MAPT 459/4885KDM4E 2767/4885THRB 3189/4885 |
| US-20120202756-A1 | USE OF PRODRUGS TO AVOID GI MEDIATED ADVERSE EVENTS | OPRM1, UGT1A6, UGT1A4 | MAPT 1661/4885KDM4E 2296/4885THRB 1496/4885 |
| US-20140241989-A1 | NOVEL IMAGING AGENTS, PROCESS FOR THE PREPARATION THEREOF AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME | C1S, C5, C1R | MAPT 1785/4885KDM4E 4718/4885THRB 4147/4885 |
| US-20240207429-A1 | LINKERS, DRUG LINKERS AND CONJUGATES THEREOF AND METHODS OF USING THE SAME | PAICS, DHFR, CD44 | MAPT 457/4885KDM4E 2160/4885THRB 3733/4885 |
| US-20120184532-A1 | GALANTAMINE AMINO ACID AND PEPTIDE PRODRUGS AND USES THEREOF | PEPD, VIP, GALR1 | MAPT 365/4885KDM4E 2154/4885THRB 486/4885 |
| US-20110065796-A1 | PRODRUGS OF GUANFACINE | DNPEP, VIP, GDA | MAPT 1107/4885KDM4E 1653/4885THRB 1455/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.