Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
| ▸ | CACNA1I | Q9P0X4 | 1/20 | 0.33 |
| ▸ | NOS3 | P29474 | 1/20 | 0.33 |
| ▸ | NOS1 | P29475 | 1/20 | 0.33 |
| ▸ | NOS2 | P35228 | 1/20 | 0.33 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.33 |
| ▸ | ALPL | P05186 | 1/20 | 0.33 |
| ▸ | PTBP1 | P26599 | 1/20 | 0.33 |
| ▸ | UGT8 | Q16880 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12545141 | 0.84 | ALDH1A1 (0.45) | ALDH1A1POLBKDM4EALOX15MAPT | |
| SCHEMBL12629021 | 0.84 | ALDH1A1 (0.39) | ALDH1A1KDM4EMAPTNR1H2RAB9A | |
| SCHEMBL5555248 | 0.76 | WNT1 (0.37) | ALDH1A1KDM4EMAPTNR1H2NPC1 | |
| SCHEMBL5551311 | 0.76 | SLC6A9 (0.37) | — | |
| SCHEMBL10261319 | 0.74 | ALDH1A1 (0.49) | ALDH1A1POLBKDM4EALOX15KCNH2 | |
| SCHEMBL17921358 | 0.74 | ALDH1A1 (0.49) | ALDH1A1POLBKDM4EALOX15KCNH2 | |
| SCHEMBL6840504 | 0.74 | ALDH1A1 (0.49) | ALDH1A1POLBKDM4EALOX15KCNH2 | |
| SCHEMBL12544596 | 0.69 | CXCR4 (0.45) | ALDH1A1POLBMAPTCYP2D6 | |
| SCHEMBL12091395 | 0.69 | ALDH1A1 (0.44) | ALDH1A1POLBKDM4EALOX15CYP3A4 | |
| SCHEMBL12091394 | 0.69 | ALDH1A1 (0.44) | ALDH1A1POLBKDM4EALOX15CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9486544-B2 | Manganese chelates and their use as contrast agents in magnetic resonance imaging (MRI) | GE HEALTHCARE AS (NO) | 2016-11-08 | — | — | US | disclosed |
| EP-2512524-B1 | MANGANESE CHELATES AND THEIR USE AS CONTRAST AGENTS IN MAGNETIC RESONANCE IMAGING (MRI) | GE HEALTHCARE AS (NO) | 2016-10-05 | — | — | EP | disclosed |
| US-20120244081-A1 | MANGANESE CHELATES AND THEIR USE AS CONTRAST AGENTS IN MAGNETIC RESONANCE IMAGING (MRI) | GE HEALTHCARE AS (NO) | 2012-09-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120244081-A1 | MANGANESE CHELATES AND THEIR USE AS CONTRAST AGENTS IN MAGNETIC RESONANCE IMAGING (MRI) | MAG, MPI, MB | ALDH1A1 4435/4885POLB 3151/4885KDM4E 1751/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.