SCHEMBL125451

SCHEMBL125451

COc1ccc(C=O)s1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18032727 0.92 TUBB4A (0.56)
SCHEMBL18032725 0.88 DPP4 (0.49)
SCHEMBL14667872 0.86 DPP4 (0.51)
SCHEMBL9050215 0.81 ALDH1A1 (0.47)
SCHEMBL14649126 0.77
SCHEMBL27492784 0.77 ALDH1A1 (0.37)
SCHEMBL11065521 0.77 ALDH1A1 (0.46)
SCHEMBL16894427 0.77 ALDH1A3 (0.42)
SCHEMBL16901839 0.77 ALDH1A1 (0.46)
SCHEMBL1763234 0.76 ALDH1A1 (0.36)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 84 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118239979-A Self-assembled monolayer material, and preparation method and application thereof 天合光能股份有限公司 2024-06-25 CN claimed
EP-4698170-A1 GLYCINAMIDE DERIVATIVES FOR USE IN THE TREATMENT OF SALMONELLOSIS Eberhard-Karls-Universität Tübingen (DE) 2026-02-25 EP disclosed
CN-120118124-A Nitrogen-rich DOPO-based flame retardant, synthesis and application thereof 常州大学 2025-06-10 CN disclosed
US-20250145601-A1 NOVEL BICYCLIC COMPOUNDS AS RAD51 INHIBITORS SATYA THERAPEUTICS, INC. 2025-05-08 US disclosed
CN-119320366-A Substituted naphthalene methyl oxadiazole-aniline compound and application thereof 中国医学科学院药物研究所 2025-01-17 CN disclosed
EP-4482831-A1 NOVEL BICYCLIC COMPOUNDS AS RAD51 INHIBITORS Satya Therapeutics, Inc. (US) 2025-01-01 EP disclosed
WO-2024218333-A1 GLYCINAMIDE DERIVATIVES FOR USE IN THE TREATMENT OF SALMONELLOSIS EBERHARD KARLS UNIVERSITÄT TÜBINGEN MEDIZINISCHE FAKULTÄT (DE) 2024-10-24 WO disclosed
CN-118696034-A Novel bicyclic compounds as RAD51 inhibitors 萨提亚疗法股份有限公司 2024-09-24 CN disclosed
US-12037531-B2 Photoresponsive high-molecular weight material, adhesive, toner, and image forming method Konica Minolta, Inc. (JP) 2024-07-16 US disclosed
CN-118239979-A Self-assembled monolayer material, and preparation method and application thereof 天合光能股份有限公司 2024-06-25 CN disclosed
EP-0540673-A4 1994-04-27 EP disclosed
EP-0540673-A1 ACETYLENE DERIVATIVES HAVING LIPOXYGENASE INHIBITORY ACTIVITY. ABBOTT LAB (US) 1993-05-12 EP disclosed
US-5100911-A Antiarrhythmic agents EBEWE ARZNEIMITTEL GESELLSCHAFT M.B.H. (AT) 1992-03-31 US disclosed
WO-1992001682-A1 ACETYLENE DERIVATIVES HAVING LIPOXYGENASE INHIBITORY ACTIVITY ABBOTT LABORATORIES (US) 1992-02-06 WO disclosed
US-4760147-A Isopropyl 1,4-dihydro-2,6-dimethyl-4-(2,3-dichlorophenyl)-3-(1,3,4-oxadiazol-2 -yl)pyridine-5-carboxylate CASSELLA AKTIENGESELLSCHAFT (DE) 1988-07-26 US disclosed
US-4681891-A Dihydro-2,6-dimethyl pyridines, formulations and method of use for treating angina pectoris, high blood pressure or disturbances of cerebral or peripheral blood flow CASSELLA AKTIENGESELLSCHAFT (DE) 1987-07-21 US disclosed
EP-0183091-A2 1,4-Dihydropyridines, process for their preparation and their use CASSELLA Aktiengesellschaft (DE) 1986-06-04 EP disclosed
EP-0172509-A2 Process for the preparation of optically active, substituted 1,4-dihydropyridines and their use as medicaments CASSELLA Aktiengesellschaft (DE) 1986-02-26 EP disclosed
US-4558058-A HYPOTENSIVE AGENTS CASSELLA AKTIENGESELLSCHAFT (DE) 1985-12-10 US disclosed
EP-0116708-A1 Substituted 1,4-dihydropyridines, method for their preparation and their use as pharmaceuticals CASSELLA Aktiengesellschaft (DE) 1984-08-29 EP disclosed