SCHEMBL12552015

SCHEMBL12552015

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nearest known ligand 0.40

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
SERPINC1 P01008 3/20 0.40
FGF1 P05230 4/20 0.39
HPSE Q9Y251 6/20 0.36
FGF2 P09038 1/20 0.36
F10 P00742 5/20 0.34
F2 P00734 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12552013 0.94 SERPINC1 (0.39) SERPINC1FGF1HPSEFGF2F10
SCHEMBL15127138 0.94 SERPINC1 (0.39) SERPINC1FGF1HPSEFGF2F10
SCHEMBL12552044 0.93 SERPINC1 (0.39) SERPINC1FGF1HPSEFGF2F10
SCHEMBL14039158 0.89 SERPINC1 (0.35) SERPINC1FGF1HPSEFGF2F10
SCHEMBL15127151 0.85 FGF1 (0.36) SERPINC1FGF1HPSEFGF2F10
SCHEMBL12551994 0.85 SERPINC1 (0.38) SERPINC1FGF1HPSEFGF2F10
SCHEMBL14039089 0.85 SERPINC1 (0.38) SERPINC1FGF1HPSEFGF2F10
SCHEMBL18539806 0.82 FGF1 (0.50) SERPINC1FGF1HPSEFGF2F10
SCHEMBL18826197 0.80 FGF1 (0.54) SERPINC1FGF1HPSEFGF2F10
SCHEMBL12551998 0.79 SERPINC1 (0.34) SERPINC1FGF1FGF2F10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8318696-B2 Polysaccharides with antithrombotic activity comprising at least one covalent bond with biotin or a biotin derivative SANOFI (FR) 2012-11-27 US disclosed
US-20110144042-A1 Novel Polysaccharides with Antithrombotic Activity Comprising at Least One Covalent Bond with Biotin or a Biotin Derivative SANOFI-AVENTIS (FR) 2011-06-16 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110144042-A1 Novel Polysaccharides with Antithrombotic Activity Comprising at Least One Covalent Bond with Biotin or a Biotin Derivative SERPINC1, SELP, FGB SERPINC1 1/4885FGF1 3910/4885HPSE 71/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.