SCHEMBL1255310

SCHEMBL1255310

C[Si](C)(Cl)CCCOc1ccc(C(=O)c2ccccc2)cc1

nearest known ligand 0.60

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
GAA P10253 1/20 0.60
PPARA Q07869 3/20 0.60
L3MBTL1 Q9Y468 4/20 0.56
LMNA P02545 3/20 0.56
MAPT P10636 2/20 0.56
MAPK1 P28482 1/20 0.55
PPARG P37231 3/20 0.52
PPARD Q03181 1/20 0.52
KDM4E B2RXH2 3/20 0.51
LTA4H P09960 1/20 0.51
HRH4 Q9H3N8 1/20 0.51
ALDH1A1 P00352 3/20 0.50
LSS P48449 2/20 0.50
HTT P42858 1/20 0.50
SMN1; SMN2 Q16637 1/20 0.50
PKM P14618 1/20 0.49
ELANE P08246 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8647078 0.91 GAA (0.60) GAAPPARAL3MBTL1LMNAMAPT
SCHEMBL12974381 0.88 GAA (0.64) GAAPPARAL3MBTL1LMNAMAPT
SCHEMBL17732445 0.84 GAA (0.59) GAAPPARAL3MBTL1LMNAMAPT
SCHEMBL14012499 0.83 GAA (0.57) GAAPPARAL3MBTL1LMNAMAPT
SCHEMBL8646278 0.83 GAA (0.57) GAAPPARAL3MBTL1LMNAMAPT
SCHEMBL2798805 0.82 L3MBTL1 (0.63) GAAPPARAL3MBTL1LMNAMAPT
SCHEMBL523003 0.82 KCNA3 (0.58) L3MBTL1LTA4HALDH1A1
SCHEMBL11485988 0.82 PPARA (0.83) GAAPPARAL3MBTL1LMNAMAPT
SCHEMBL4561660 0.82 GAA (0.79) GAAPPARAL3MBTL1LMNAMAPT
SCHEMBL1469758 0.81 GAA (0.72) GAAPPARAL3MBTL1LMNAMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 113 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3452524-B1 WATER VAPOR-BLOCKING ADHESIVE COMPOUND HAVING HIGHLY FUNCTIONALIZED POLY(METH)ACRYLATE TESA SE (DE) 2021-03-03 EP claimed
WO-2003099348-A1 STENT COMPRISING A COVALENTLY BONDED MONOLAYER BIOTRONIK MESS- UND THERAPIEGERÄTE GMBH & CO. (DE) 2003-12-04 WO claimed
US-12599322-B2 Method for an analyte sensor cover-membrane preparation ROCHE DIABETES CARE, INC. (US) 2026-04-14 US disclosed
EP-3735903-B1 METHOD FOR AN ANALYTE SENSOR COVER-MEMBRANE PREPARATION ROCHE DIABETES CARE GMBH (DE) 2025-11-05 EP disclosed
EP-3212727-B1 ADHESIVE COMPOUNDS CONTAINING GETTER MATERIALS THAT CAN BE ACTIVATED TESA SE (DE) 2025-03-05 EP disclosed
CN-114380929-B Functionalized (co) polymers for adhesive systems 德莎欧洲股份公司 2024-02-06 CN disclosed
EP-3452522-B1 FUNCTIONALIZED (CO)POLYMERS FOR ADHESIVE SYSTEMS TESA SE (DE) 2023-12-13 EP disclosed
CN-113166594-B Potentially reactive adhesive film 德莎欧洲股份公司 2023-08-01 CN disclosed
US-11680192-B2 Functionalized (co)polymers for adhesive systems TESA SE (DE) 2023-06-20 US disclosed
EP-3481888-B1 CURABLE ADHESIVE COMPOUND AND REACTIVE ADHESIVE TAPES BASED THEREON TESA SE (DE) 2023-03-29 EP disclosed
US-11447669-B2 Water vapor-blocking adhesive compound having highly functionalized poly(meth)acrylate TESA SE (DE) 2022-09-20 US disclosed
US-20070116607-A1 Microsystems that integrate three-dimensional microarray and multi-layer microfluidics for combinatorial detection of bioagent at single molecule level PHARMACOM MICROLELECTRONICS, INC. (US) 2007-05-24 US disclosed
US-20070026038-A1 Method of Coating a Stent with a Polysaccharide Layer and Associated Stents BIOTRONIK MESS- UND THERAPIEGERAETE GMBH & CO. (DE) 2007-02-01 US disclosed
US-20060257650-A1 Pressure-sensitive adhesives and process for preparing them TESA AKTIENGESELLSCHAFT (DE) 2006-11-16 US disclosed
WO-2006120136-A2 PRESSURE-SENSITIVE ADHESIVE MASS AND METHOD FOR THE PRODUCTION THEREOF TESA AG (DE) 2006-11-16 WO disclosed
WO-2005118020-A1 SURFACE COATING COMPRISING BIOACTIVE COMPOUND ALLVIVO, INC. (US) 2005-12-15 WO disclosed
US-20050244456-A1 Surface coating comprising bioactive compound NAGLER, RICHARD, MR. 2005-11-03 US disclosed
US-20040091605-A1 Method of coating a stent with a polysaccharide layer and associated stents BIOTRONIK MESS- UND THERAPIEGERAETE GMBH & CO INGENIEURBUERO BERLIN 2004-05-13 US disclosed
WO-2003099348-A1 STENT COMPRISING A COVALENTLY BONDED MONOLAYER BIOTRONIK MESS- UND THERAPIEGERÄTE GMBH & CO. (DE) 2003-12-04 WO disclosed
EP-1364664-A1 Process for coating a stent with a polysaccharide layer and stent made with a such process BIOTRONIK Mess- und Therapiegeräte GmbH & Co Ingenieurbüro Berlin (DE) 2003-11-26 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050244456-A1 Surface coating comprising bioactive compound C5AR1, C3AR1, C1QBP GAA 3137/4885PPARA 4145/4885L3MBTL1 3125/4885
US-12599322-B2 Method for an analyte sensor cover-membrane preparation F10, S100A10, EPCAM GAA 4232/4885PPARA 2804/4885L3MBTL1 4881/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.