Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Lithium Ion. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | APEX1 | P27695 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23607566 | 0.98 | THRB (0.50) | THRBTSHRALDH1A1POLBAPEX1 | |
| SCHEMBL434885 | 0.96 | THRB (0.48) | THRBTSHRALDH1A1POLBAPEX1 | |
| Potassium Ion SCHEMBL18140214 | 0.96 | THRB (0.48) | THRBTSHRALDH1A1POLBAPEX1 | |
| SCHEMBL25286189 | 0.96 | THRB (0.48) | THRBTSHRALDH1A1POLBAPEX1 | |
| Methacrylic Acid SCHEMBL9136484 | 0.91 | THRB (0.44) | THRBTSHRALDH1A1POLBAPEX1 | |
| Lithium Ion SCHEMBL16628565 | 0.89 | TSHR (0.53) | THRBTSHRALDH1A1POLBAPEX1 | |
| Lithium Ion SCHEMBL18139781 | 0.87 | TSHR (0.56) | THRBTSHRALDH1A1POLBAPEX1 | |
| SCHEMBL23607561 | 0.87 | TSHR (0.55) | THRBTSHRALDH1A1POLBAPEX1 | |
| SCHEMBL1876760 | 0.87 | CHRM5 (0.49) | THRBTSHRAPEX1 | |
| Lithium Ion SCHEMBL3396120 | 0.86 | TSHR (0.59) | THRBTSHRALDH1A1POLBAPEX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5212622-A | Crosslinked binder | SPECIALIZED CONDUCTIVES PTY. LTD. (AU) | 1993-05-18 | — | — | US | claimed |
| CN-112638519-B | stationary phase for chromatography | 株式会社大赛璐 | 2023-11-10 | — | — | CN | disclosed |
| US-20210252479-A1 | STATIONARY PHASE FOR CHROMATOGRAPHY | DAICEL CORPORATION (JP) | 2021-08-19 | — | — | US | disclosed |
| EP-3845307-A1 | STATIONARY PHASE FOR CHROMATOGRAPHY | Daicel Corporation (JP) | 2021-07-07 | — | — | EP | disclosed |
| CN-112638519-A | Stationary phase for chromatography | 株式会社大赛璐 | 2021-04-09 | — | — | CN | disclosed |
| WO-2020045648-A1 | STATIONARY PHASE FOR CHROMATOGRAPHY | 株式会社ダイセル | 2020-03-05 | — | — | WO | disclosed |
| US-9217052-B2 | Copolymer | NIPPON SODA CO., LTD. (JP) | 2015-12-22 | — | — | US | disclosed |
| US-9115239-B2 | Copolymer | NIPPON SODA CO., LTD. (JP) | 2015-08-25 | — | — | US | disclosed |
| EP-2559715-B1 | NOVEL COPOLYMER | NIPPON SODA CO (JP) | 2015-02-25 | — | — | EP | disclosed |
| US-8461237-B2 | Gel composition, method of preparing the same, and impact resistant absorbing material using the same | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2013-06-11 | — | — | US | disclosed |
| EP-2559715-A1 | NOVEL COPOLYMER | Nippon Soda Co., Ltd. (JP) | 2013-02-20 | — | — | EP | disclosed |
| US-20130023628-A1 | NOVEL COPOLYMER | NIPPON SODA CO., LTD. (JP) | 2013-01-24 | — | — | US | disclosed |
| EP-2387866-A1 | ELECTROMAGNETIC WAVE SHIELDING GEL-LIKE COMPOSITION | 3M Innovative Properties Company (US) | 2011-11-23 | — | — | EP | disclosed |
| US-20110268950-A1 | Electromagnetic Wave Shielding Gel-Like Composition | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2011-11-03 | — | — | US | disclosed |
| US-8038066-B2 | Laser scanner with deformable lens | HAND HELD PRODUCTS, INC. (US) | 2011-10-18 | — | — | US | disclosed |
| US-20110097585-A1 | GEL COMPOSITION, METHOD OF PREPARING THE SAME, AND IMPACT RESISTANT ABSORBING MATERIAL USING THE SAME | 3M INNOVATIVE PROPERTIES COMPANY | 2011-04-28 | — | — | US | disclosed |
| EP-2285900-A2 | GEL COMPOSITION, METHOD FOR PREPARING THE SAME, AND IMPACT RESISTANT ABSORBING MATERIAL USING THE SAME | 3M Innovative Properties Company (US) | 2011-02-23 | — | — | EP | disclosed |
| WO-2010083075-A1 | ELECTROMAGNETIC WAVE SHIELDING GEL-LIKE COMPOSITION | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2010-07-22 | — | — | WO | disclosed |
| WO-2009134694-A2 | GEL COMPOSITION, METHOD FOR PREPARING THE SAME, AND IMPACT RESISTANT ABSORBING MATERIAL USING THE SAME | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2009-11-05 | — | — | WO | disclosed |
| US-5212622-A | Crosslinked binder | SPECIALIZED CONDUCTIVES PTY. LTD. (AU) | 1993-05-18 | — | — | US | disclosed |