Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Lithium Ion. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.53 |
| ▸ | THRB | P10828 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | APEX1 | P27695 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.36 |
| ▸ | BBOX1 | O75936 | 2/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | GMNN | O75496 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | THPO | P40225 | 1/20 | 0.32 |
| ▸ | HBB | P68871 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23607561 | 0.98 | TSHR (0.55) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL345585 | 0.96 | TSHR (0.53) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL16628478 | 0.96 | TSHR (0.53) | TSHRTHRBPOLBAPEX1HTT | |
| Potassium Ion SCHEMBL379532 | 0.96 | TSHR (0.53) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL16628613 | 0.96 | TSHR (0.53) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL16628435 | 0.96 | TSHR (0.53) | TSHRTHRBPOLBAPEX1HTT | |
| Lithium Ion SCHEMBL18139781 | 0.95 | TSHR (0.56) | TSHRTHRBPOLBAPEX1HTT | |
| Methacrylic Acid SCHEMBL18065079 | 0.93 | TSHR (0.50) | TSHRTHRBPOLBAPEX1HTT | |
| Lithium Ion SCHEMBL3396120 | 0.93 | TSHR (0.59) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL18139287 | 0.91 | TSHR (0.56) | TSHRTHRBPOLBAPEX1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250250384-A1 | BIO-BASED POLYMERS FROM RAW LIGNOCELLULOSIC BIOMASS | UNIVERSITY OF DELAWARE | 2025-08-07 | — | — | US | claimed |
| US-12291592-B2 | Ion-conducting bio-based polymers from raw lignocellulosic biomass | UNIVERSITY OF DELAWARE (US) | 2025-05-06 | — | — | US | claimed |
| US-20230113164-A1 | BIO-BASED POLYMERS FROM RAW LIGNOCELLULOSIC BIOMASS | UNIVERSITY OF DELAWARE (US) | 2023-04-13 | — | — | US | claimed |
| US-20250250384-A1 | BIO-BASED POLYMERS FROM RAW LIGNOCELLULOSIC BIOMASS | UNIVERSITY OF DELAWARE | 2025-08-07 | — | — | US | disclosed |
| US-12291592-B2 | Ion-conducting bio-based polymers from raw lignocellulosic biomass | UNIVERSITY OF DELAWARE (US) | 2025-05-06 | — | — | US | disclosed |
| CN-112638519-B | stationary phase for chromatography | 株式会社大赛璐 | 2023-11-10 | — | — | CN | disclosed |
| US-20230113164-A1 | BIO-BASED POLYMERS FROM RAW LIGNOCELLULOSIC BIOMASS | UNIVERSITY OF DELAWARE (US) | 2023-04-13 | — | — | US | disclosed |
| CN-115663186-A | Single-ion conductor polymer modified negative electrode material and preparation method and application thereof | 溧阳天目先导电池材料科技有限公司 | 2023-01-31 | — | — | CN | disclosed |
| US-11525024-B2 | Bio-based polymers from raw lignocellulosic biomass | UNIVERSITY OF DELAWARE (US) | 2022-12-13 | — | — | US | disclosed |
| US-20210252479-A1 | STATIONARY PHASE FOR CHROMATOGRAPHY | DAICEL CORPORATION (JP) | 2021-08-19 | — | — | US | disclosed |
| EP-3845307-A1 | STATIONARY PHASE FOR CHROMATOGRAPHY | Daicel Corporation (JP) | 2021-07-07 | — | — | EP | disclosed |
| CN-112638519-A | Stationary phase for chromatography | 株式会社大赛璐 | 2021-04-09 | — | — | CN | disclosed |
| WO-2020045648-A1 | STATIONARY PHASE FOR CHROMATOGRAPHY | 株式会社ダイセル | 2020-03-05 | — | — | WO | disclosed |
| US-20180163056-A1 | HYDROPHILIC CURABLE COMPOSITIONS | MITSUI CHEMICALS, INC. (JP) | 2018-06-14 | — | — | US | disclosed |
| US-20180036995-A1 | HYDROPHILIC MONOLAYER FILM WITH OPTICAL FUNCTIONALITY AND STACK OF THE SAME | MITSUI CHEMICALS, INC. (JP) | 2018-02-08 | — | — | US | disclosed |
| EP-3270192-A1 | HYDROPHILIC SINGLE-LAYER FILM HAVING OPTICAL FUNCTIONALITY, AND LAMINATE THEREOF | Mitsui Chemicals, Inc. (JP) | 2018-01-17 | — | — | EP | disclosed |
| EP-3081578-A1 | COMPOSITION FOR HYDROPHILIC CURED PRODUCT | Mitsui Chemicals, Inc. (JP) | 2016-10-19 | — | — | EP | disclosed |
| US-20150126682-A1 | HYDROPHILIC MODIFIED ACRYLIC RESIN FILM | MITSUI CHEMICALS, INC. (JP) | 2015-05-07 | — | — | US | disclosed |
| EP-2860215-A1 | MODIFIED HYDROPHILIC ACRYLIC RESIN FILM | Mitsui Chemicals, Inc. (JP) | 2015-04-15 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12291592-B2 | Ion-conducting bio-based polymers from raw lignocellulosic biomass | ME1, FHIT, BOLA2; BOLA2B | TSHR 4833/4885THRB 3455/4885POLB 3533/4885 |
| US-20250250384-A1 | BIO-BASED POLYMERS FROM RAW LIGNOCELLULOSIC BIOMASS | ME1, BLVRB, FHIT | TSHR 4858/4885THRB 3708/4885POLB 2866/4885 |
| US-20230113164-A1 | BIO-BASED POLYMERS FROM RAW LIGNOCELLULOSIC BIOMASS | ME1, BLVRB, FHIT | TSHR 4845/4885THRB 3606/4885POLB 2691/4885 |
| US-11525024-B2 | Bio-based polymers from raw lignocellulosic biomass | ME1, BLVRB, PLOD1 | TSHR 4884/4885THRB 4250/4885POLB 2183/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.