Known targets — ChEMBL curated mechanism
ABCC8ACEADORA1ADORA2AADORA2BADORA3ALDH5A1ALOX5ALOX5APATP4AATP4BBRAFCA1CA12CA2CA4CYSLTR1DHFRDPEP1EDNRAEDNRBESR2F10FDPSFGF1GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTGNRHRGSC1HMGCRIMPDH1IMPDH2KCNJ11LY96NOD2NR3C1NS3NS4ANS5bP2RY1P2RY12P2RY2P2RY4P2RY6PBP2XPDE3APDE3BPDE4APDE4BPDE4CPDE4DPDK1PDK2PDK3PDK4PPARGPPATPTGIRPTGS1PTGS2RAF1RYR1RYR3SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASERPINC1SLC12A1SLC12A3SYKTHRATHRBTLR3TLR4TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYMSVKORC1XDHblablaIMP-1blaOXA-33blaOXA-58blaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAfolPfolP1ftsIfusAgaggyrAgyrBmecAmrcAmrcBmrdApbp1apbp1bpbp2pbp2apbp2bpbp3pbp4pbpApbpBpbpCpbpFpolponBrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpoArpoBrpoCrpoZrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB known ✓ | P10828 | 1/20 | 0.48 |
| ▸ | CA2 known ✓ | P00918 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 4/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | APEX1 | P27695 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | GMNN | O75496 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | THPO | P40225 | 1/20 | 0.30 |
| ▸ | HBB | P68871 | 1/20 | 0.30 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23607566 | 0.98 | THRB (0.50) | THRBTSHRALDH1A1POLBAPEX1 | |
| Potassium Ion SCHEMBL18140214 | 0.96 | THRB (0.48) | THRBTSHRALDH1A1POLBAPEX1 | |
| Lithium Ion SCHEMBL1255355 | 0.96 | THRB (0.48) | THRBTSHRALDH1A1POLBAPEX1 | |
| SCHEMBL25286189 | 0.96 | THRB (0.48) | THRBTSHRALDH1A1POLBAPEX1 | |
| Methacrylic Acid SCHEMBL9136484 | 0.95 | THRB (0.44) | THRBTSHRALDH1A1POLBAPEX1 | |
| SCHEMBL18139533 | 0.90 | THRB (0.56) | THRBTSHRALDH1A1POLBAPEX1 | |
| SCHEMBL16628465 | 0.90 | THRB (0.56) | THRBTSHRALDH1A1POLBAPEX1 | |
| SCHEMBL345585 | 0.89 | TSHR (0.53) | THRBTSHRALDH1A1POLBAPEX1 | |
| SCHEMBL8746515 | 0.87 | TSHR (0.56) | THRBTSHRALDH1A1POLBAPEX1 | |
| SCHEMBL23607561 | 0.87 | TSHR (0.55) | THRBTSHRALDH1A1POLBAPEX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 201 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118930119-A | Mortar additive and preparation process thereof | 江苏先帅科技有限公司 | 2024-11-12 | — | — | CN | claimed |
| CN-118812777-A | Anhydride-containing sulfonyl/phosphonyl copolymer and preparation method and application thereof | 四川大学 | 2024-10-22 | — | — | CN | claimed |
| CN-118667067-A | Copolymer, preparation method and application thereof, and drilling fluid | 中国石油化工股份有限公司 | 2024-09-20 | — | — | CN | claimed |
| US-20230365732-A1 | BINDER AND LITHIUM-ION BATTERY COMPRISING SAME | ZHUHAI COSMX BATTERY CO., LTD. (CN) | 2023-11-16 | — | — | US | claimed |
| CN-113527575-B | Hyperbranched polymer fluid loss additive synthesized from pentaerythritol polyene monomer and preparation method thereof | 长江大学 | 2022-09-06 | — | — | CN | claimed |
| CN-114829424-A | Aqueous latex of vinylidene chloride copolymer | 索尔维公司 | 2022-07-29 | — | — | CN | claimed |
| CN-113527575-A | Hyperbranched polymer filtrate reducer synthesized from pentaerythritol polyene monomer and preparation method thereof | 长江大学 | 2021-10-22 | — | — | CN | claimed |
| EP-0539729-B1 | Development inhibitor reflector layers | EASTMAN KODAK CO (US) | 1998-07-15 | — | — | EP | claimed |
| EP-0621325-B1 | Room temperature curing composition | KANEGAFUCHI CHEMICAL IND (JP) | 1997-12-29 | — | — | EP | claimed |
| US-5668194-A | SHELL-CORE POLYMER FROM UNSATURATED SILICON MONOMER | KANEGAFUCHI CHEMICAL INDUSTRY CO., LTD. (JP) | 1997-09-16 | — | — | US | claimed |
| US-4990435-A | Stable polymeric coating | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1991-02-05 | — | — | US | claimed |
| EP-0226129-B1 | SILVER HALIDE PHOTOGRAPHIC ELEMENT, PHOTOGRAPHIC COATING COMPOSITION AND PROCESS TO PREPARE AN AQUEOUS DISPERSION OF A HYDROPHOBIC COMPOUND | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1990-05-23 | — | — | EP | claimed |
| EP-0187984-B1 | POLYMERIC MORDANT CONTAINING NITROGEN-COORDINATING LIGAND FOR METALLIZABLE DYES | EASTMAN KODAK COMPANY (a New Jersey corporation) (US) | 1988-11-09 | — | — | EP | claimed |
| US-4678819-A | CASTING POLYMERIZATION | MITSUBISHI RAYON CO., LTD. (JP) | 1987-07-07 | — | — | US | claimed |
| EP-0226129-A2 | Silver halide photographic element, photographic coating composition and process to prepare an aqueous dispersion of a hydrophobic compound | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1987-06-24 | — | — | EP | claimed |
| EP-0187984-A1 | Polymeric mordant containing nitrogen-coordinating ligand for metallizable dyes | EASTMAN KODAK COMPANY (a New Jersey corporation) (US) | 1986-07-23 | — | — | EP | claimed |
| US-4599389-A | COLOR PHOTOGRAPHY DIFFUSION TRANSFER | EASTMAN KODAK COMPANY (US) | 1986-07-08 | — | — | US | claimed |
| US-4581314-A | FOR COLOR DIFFUSION TRANSFER PHOTOGRAPHY; RAPID DYE METALLIZATION | EASTMAN KODAK COMPANY (US) | 1986-04-08 | — | — | US | claimed |
| US-4480025-A | Water reservoir layers in bleach-fix sheets | EASTMAN KODAK COMPANY (US) | 1984-10-30 | — | — | US | claimed |
| US-4217260-A | SHELL-CORE POLYMERS WITH AMINOPHENYLTHIO-GROUPS | RHONE-POULENC INDUSTRIES (FR) | 1980-08-12 | — | — | US | claimed |