Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.35 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.35 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.35 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.35 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.35 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.35 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.35 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.35 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.35 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.35 |
| ▸ | NAMPT | P43490 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | FAAH | O00519 | 1/20 | 0.33 |
| ▸ | ABHD16A | O95870 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL181009 | 1.00 | SMN1; SMN2 (0.41) | SMN1; SMN2HPGDHTTHDAC3HDAC4 | |
| SCHEMBL2734922 | 0.99 | SMN1; SMN2 (0.39) | SMN1; SMN2HPGDHTTHDAC3HDAC4 | |
| SCHEMBL180975 | 0.97 | SMN1; SMN2 (0.45) | SMN1; SMN2HPGDHTTHDAC3HDAC4 | |
| SCHEMBL8663263 | 0.94 | SMN1; SMN2 (0.37) | SMN1; SMN2HPGDHTTLMNA | |
| SCHEMBL26382038 | 0.90 | SMN1; SMN2 (0.50) | SMN1; SMN2HPGDHTTHDAC3HDAC4 | |
| SCHEMBL17767812 | 0.90 | SMN1; SMN2 (0.50) | SMN1; SMN2HPGDHTTHDAC3HDAC4 | |
| SCHEMBL17767809 | 0.90 | SMN1; SMN2 (0.50) | SMN1; SMN2HPGDHTTHDAC3HDAC4 | |
| SCHEMBL20999873 | 0.90 | SMN1; SMN2 (0.50) | SMN1; SMN2HPGDHTTHDAC3HDAC4 | |
| SCHEMBL17168743 | 0.90 | SMN1; SMN2 (0.50) | SMN1; SMN2HPGDHTTHDAC3HDAC4 | |
| SCHEMBL31128140 | 0.89 | EPHX2 (0.45) | SMN1; SMN2KMT2AEPHX2CASP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9242011-B2 | Insulin albumin conjugates | NOVO NORDISK A/S (DK) | 2016-01-26 | — | — | US | disclosed |
| EP-2262539-B1 | INSULIN ALBUMIN CONJUGATES | NOVO NORDISK AS (DK) | 2015-07-15 | — | — | EP | disclosed |
| US-20110039769-A1 | INSULIN ALBUMIN CONJUGATES | NOVO NORDISK A/S (DK) | 2011-02-17 | — | — | US | disclosed |
| EP-2262539-A1 | INSULIN ALBUMIN CONJUGATES | Novo Nordisk A/S (DK) | 2010-12-22 | — | — | EP | disclosed |
| WO-2009121884-A1 | INSULIN ALBUMIN CONJUGATES | NOVO NORDISK A/S (DK) | 2009-10-08 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110039769-A1 | INSULIN ALBUMIN CONJUGATES | ALB, IAPP, IGFBP1 | SMN1; SMN2 2279/4885HPGD 3791/4885HTT 946/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.