SCHEMBL180975

SCHEMBL180975

O=C(CI)NCCCCCC(=O)NCCCCCC(=O)ON1C(=O)CCC1=O

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 2/20 0.45
HPGD P15428 1/20 0.45
HTT P42858 1/20 0.45
ALDH1A1 P00352 1/20 0.36
HDAC3 O15379 3/20 0.36
HDAC4 P56524 3/20 0.36
HDAC1 Q13547 3/20 0.36
HDAC7 Q8WUI4 3/20 0.36
HDAC2 Q92769 3/20 0.36
HDAC10 Q969S8 3/20 0.36
HDAC11 Q96DB2 3/20 0.36
HDAC8 Q9BY41 3/20 0.36
HDAC6 Q9UBN7 3/20 0.36
HDAC9 Q9UKV0 3/20 0.36
HDAC5 Q9UQL6 3/20 0.36
L3MBTL1 Q9Y468 1/20 0.35
NAMPT P43490 4/20 0.34
ACHE P22303 2/20 0.33
CASP2 P42575 1/20 0.33
BCHE P06276 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL181009 0.97 SMN1; SMN2 (0.41) SMN1; SMN2HPGDHTTALDH1A1HDAC3
SCHEMBL1255461 0.97 SMN1; SMN2 (0.41) SMN1; SMN2HPGDHTTALDH1A1HDAC3
SCHEMBL2734922 0.96 SMN1; SMN2 (0.39) SMN1; SMN2HPGDHTTALDH1A1HDAC3
SCHEMBL17767812 0.93 SMN1; SMN2 (0.50) SMN1; SMN2HPGDHTTALDH1A1HDAC3
SCHEMBL26382038 0.93 SMN1; SMN2 (0.50) SMN1; SMN2HPGDHTTALDH1A1HDAC3
SCHEMBL20999873 0.93 SMN1; SMN2 (0.50) SMN1; SMN2HPGDHTTALDH1A1HDAC3
SCHEMBL17767809 0.93 SMN1; SMN2 (0.50) SMN1; SMN2HPGDHTTALDH1A1HDAC3
SCHEMBL17168743 0.93 SMN1; SMN2 (0.50) SMN1; SMN2HPGDHTTALDH1A1HDAC3
SCHEMBL21117960 0.92 SMN1; SMN2 (0.49) SMN1; SMN2HPGDHTTALDH1A1HDAC3
SCHEMBL8663263 0.92 SMN1; SMN2 (0.37) SMN1; SMN2HPGDHTTTSHRPOLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 220 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250352663-A1 Nanoclusters Functionalized with Adenosine Triphosphate or an Analogue and Their Use UNIV LELAND STANFORD JUNIOR (US) 2025-11-20 US disclosed
US-11998615-B2 Functionalized nanoparticles and their use in treating bacterial infections THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) 2024-06-04 US disclosed
US-20240148882-A1 METHODS OF TREATING AN OCULAR DISEASE OR DISORDER THE REGENTS OF THE UNIVERSITY OF CALIFORNIA 2024-05-09 US disclosed
WO-2024044636-A2 NANOCLUSTERS FUNCTIONALIZED WITH ADENOSINE TRIPHOSPHATE OR AN ANALOGUE AND THEIR USE THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) 2024-02-29 WO disclosed
WO-2023164224-A1 FUNCTIONALIZED NANOCLUSTERS AND THEIR USE IN TREATING BACTERIAL INFECTIONS THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) 2023-08-31 WO disclosed
US-11723982-B2 Methods of treating an ocular disease or disorder THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2023-08-15 US disclosed
US-20230149561-A1 Functionalized Nanoparticles and Their Use in Treating Bacterial Infections THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY 2023-05-18 US disclosed
US-20220339293-A1 FUNCTIONALIZED NANOPARTICLES AND THEIR USE IN TREATING BACTERIAL INFECTIONS THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY 2022-10-27 US disclosed
US-20220265763-A1 POLYPEPTIDE-POLYMER CONJUGATES AND METHODS OF USE THEREOF UNIV CALIFORNIA (US) 2022-08-25 US disclosed
US-20220227855-A1 COMPOSITIONS AND METHODS FOR TREATMENT OF ANGIOGENESIS RELATED DISEASES THE UNIVERSITY OF MASSACHUSETTS 2022-07-21 US disclosed
US-20040115168-A1 Interferon beta: remodeling and glycoconjugation of interferon beta NEOSE TECHNOLOGIES, INC. 2004-06-17 US disclosed
US-20040082026-A1 Interferon alpha: remodeling and glycoconjugation of interferon alpha NEOSE TECHNOLOGIES, INC. 2004-04-29 US disclosed
US-20040077836-A1 Granulocyte colony stimulating factor: remodeling and glycoconjugation of G-CSF NEOSE TECHNOLOGIES, INC. 2004-04-22 US disclosed
WO-2004033651-A2 ERYTHROPOIETIN: REMODELING AND GLYCOCONJUGATION OF ERYTHROPOIETIN NEOSE TECHNOLOGIES, INC. (US) 2004-04-22 WO disclosed
US-20040063911-A1 Protein remodeling methods and proteins/peptides produced by the methods NEOSE TECHNOLOGIES, INC. 2004-04-01 US disclosed
US-20040043446-A1 Alpha galalctosidase a: remodeling and glycoconjugation of alpha galactosidase A NEOSE TECHNOLOGIES, INC. 2004-03-04 US disclosed
US-20040001892-A1 Tunable, semi-interpenetrating polymer networks (sIPNS) for medicine and biotechnology THE REGENTS OF THE UNIVERSITY OF CALIFORNIA 2004-01-01 US disclosed
WO-2003031464-A2 REMODELING AND GLYCOCONJUGATION OF PEPTIDES NEOSE TECHNOLOGIES, INC. (US) 2003-04-17 WO disclosed
EP-1218413-A2 ENGINEERING ANTIBODIES THAT BIND IRREVERSIBLY The Regents of the University of California (US) 2002-07-03 EP disclosed
WO-2001022922-A2 ENGINEERING ANTIBODIES THAT BIND IRREVERSIBLY THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2001-04-05 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040077836-A1 Granulocyte colony stimulating factor: remodeling and glycoconjugation of G-CSF CSF3R, CSF1R, GMFG SMN1; SMN2 4204/4885HPGD 2582/4885HTT 3557/4885
US-20040082026-A1 Interferon alpha: remodeling and glycoconjugation of interferon alpha IFNG, IFNAR1, IRF3 SMN1; SMN2 4636/4885HPGD 2358/4885HTT 4331/4885
US-20040063911-A1 Protein remodeling methods and proteins/peptides produced by the methods PTMS, ANPEP, SMURF1 SMN1; SMN2 4161/4885HPGD 4080/4885HTT 1745/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.