Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 4/20 | 0.56 |
| ▸ | LMNA | P02545 | 4/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.56 |
| ▸ | TP53 | P04637 | 1/20 | 0.56 |
| ▸ | THRB | P10828 | 1/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.56 |
| ▸ | TSHR | P16473 | 3/20 | 0.53 |
| ▸ | ACHE | P22303 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | RELA | Q04206 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | TEAD4 | Q15561 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL258632 | 0.88 | CYP3A4 (0.58) | CYP3A4LMNAALDH1A1HSD17B10MAPK1 | |
| SCHEMBL14678662 | 0.85 | ALDH1A1 (0.51) | CYP3A4LMNAALDH1A1HSD17B10MAPK1 | |
| SCHEMBL5850251 | 0.80 | CYP3A4 (0.50) | CYP3A4LMNAALDH1A1HSD17B10MAPK1 | |
| SCHEMBL1605116 | 0.80 | MEN1 (0.50) | CYP3A4LMNAALDH1A1SMN1; SMN2TSHR | |
| SCHEMBL258335 | 0.80 | MEN1 (0.50) | CYP3A4LMNAALDH1A1SMN1; SMN2TSHR | |
| SCHEMBL11477739 | 0.80 | LMNA (0.55) | CYP3A4LMNAALDH1A1HSD17B10MAPK1 | |
| SCHEMBL10455273 | 0.79 | LMNA (0.53) | CYP3A4LMNAALDH1A1HSD17B10MAPK1 | |
| SCHEMBL6692402 | 0.79 | CYP3A4 (0.54) | CYP3A4LMNAALDH1A1HSD17B10MAPK1 | |
| SCHEMBL1691989 | 0.79 | CYP3A4 (0.54) | CYP3A4LMNAALDH1A1HSD17B10MAPK1 | |
| Temefos SCHEMBL23303378 | 0.78 | LMNA (0.53) | CYP3A4LMNAALDH1A1HSD17B10MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110142717-A1 | EMISSIVE SENSORS AND DEVICES INCORPORATING THESE SENSORS | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2011-06-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110142717-A1 | EMISSIVE SENSORS AND DEVICES INCORPORATING THESE SENSORS | PAXBP1, PAX3, MTAP | CYP3A4 2546/4885LMNA 1173/4885ALDH1A1 4384/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.