Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 4/20 | 0.32 |
| ▸ | MTNR1B | P49286 | 4/20 | 0.32 |
| ▸ | BUB1 | O43683 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12559771 | 0.80 | NOS1 (0.31) | — | |
| SCHEMBL12559871 | 0.80 | NOS1 (0.31) | — | |
| SCHEMBL12597886 | 0.80 | NOS1 (0.31) | — | |
| SCHEMBL12597859 | 0.69 | VIP (0.54) | — | |
| SCHEMBL12598739 | 0.68 | SCN9A (0.43) | — | |
| SCHEMBL8228215 | 0.61 | TYMS (0.36) | — | |
| SCHEMBL23165445 | 0.60 | MTNR1A (0.32) | MTNR1AMTNR1B | |
| SCHEMBL23346519 | 0.60 | MTNR1A (0.32) | MTNR1AMTNR1B | |
| SCHEMBL20685675 | 0.60 | MTNR1A (0.32) | MTNR1AMTNR1B | |
| SCHEMBL20685659 | 0.60 | MTNR1A (0.32) | MTNR1AMTNR1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9084423-B2 | Inhibition of bacterial biofilms with imidazole derivatives | NORTH CAROLINA STATE UNIVERSITY (US) | 2015-07-21 | — | — | US | disclosed |
| US-9084423-B2 | Inhibition of bacterial biofilms with imidazole derivatives | NORTH CAROLINA STATE UNIVERSITY (US) | 2015-07-21 | — | — | US | disclosed |
| US-20140127273-A1 | INHIBITION OF BACTERIAL BIOFILMS WITH IMIDAZOLE DERIVATIVES | NORTH CAROLINA STATE UNIVERSITY (US) | 2014-05-08 | — | — | US | disclosed |
| US-20140127273-A1 | INHIBITION OF BACTERIAL BIOFILMS WITH IMIDAZOLE DERIVATIVES | NORTH CAROLINA STATE UNIVERSITY (US) | 2014-05-08 | — | — | US | disclosed |
| US-8653124-B2 | Inhibition of bacterial biofilms with imidazole derivatives | NORTH CAROLINA STATE UNIVERSITY (US) | 2014-02-18 | — | — | US | disclosed |
| US-8653124-B2 | Inhibition of bacterial biofilms with imidazole derivatives | NORTH CAROLINA STATE UNIVERSITY (US) | 2014-02-18 | — | — | US | disclosed |
| US-20110150819-A1 | INHIBITION OF BACTERIAL BIOFILMS WITH IMIDAZOLE DERIVATIVES | MELANDER CHRISTIAN | 2011-06-23 | — | — | US | disclosed |
| US-20110150819-A1 | INHIBITION OF BACTERIAL BIOFILMS WITH IMIDAZOLE DERIVATIVES | MELANDER CHRISTIAN | 2011-06-23 | — | — | US | disclosed |
| US-7906544-B2 | Dentifrices; stents; catheters; grafts | NORTH CAROLINA STATE UNIVERSITY (US) | 2011-03-15 | — | — | US | disclosed |
| US-20080181923-A1 | INHIBITION OF BACTERIAL BIOFILMS WITH IMIDAZOLE DERIVATIVES | NORTH CAROLINA STATE UNIVERSITY | 2008-07-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080181923-A1 | INHIBITION OF BACTERIAL BIOFILMS WITH IMIDAZOLE DERIVATIVES | O60361, TFPI, BLVRB | MTNR1A 4755/4885MTNR1B 4598/4885BUB1 2346/4885 |
| US-20110150819-A1 | INHIBITION OF BACTERIAL BIOFILMS WITH IMIDAZOLE DERIVATIVES | O60361, TFPI, BLVRB | MTNR1A 4755/4885MTNR1B 4598/4885BUB1 2346/4885 |
| US-20140127273-A1 | INHIBITION OF BACTERIAL BIOFILMS WITH IMIDAZOLE DERIVATIVES | O60361, TFPI, BLVRB | MTNR1A 4755/4885MTNR1B 4598/4885BUB1 2346/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.