Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABBR2 | O75899 | 1/20 | 0.38 |
| ▸ | GABBR1 | Q9UBS5 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.37 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.37 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.36 |
| ▸ | DRD3 | P35462 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.36 |
| ▸ | EDNRB | P24530 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | MC4R | P32245 | 1/20 | 0.36 |
| ▸ | MC3R | P41968 | 1/20 | 0.36 |
| ▸ | DRD2 | P14416 | 1/20 | 0.36 |
| ▸ | BCAT2 | O15382 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12522057 | 0.78 | GABBR2 (0.43) | GABBR2GABBR1CYP2D6CYP1A2PKM | |
| SCHEMBL22992328 | 0.70 | AOC3 (0.45) | SMN1; SMN2ALOX5LMNAGAATAAR1 | |
| SCHEMBL13688832 | 0.70 | ALOX5 (0.44) | CYP2D6SMN1; SMN2ALOX5LMNAGAA | |
| SCHEMBL1206430 | 0.70 | ALOX5 (0.44) | CYP2D6SMN1; SMN2ALOX5LMNAGAA | |
| SCHEMBL27701679 | 0.70 | HPGD (0.46) | CYP2D6CYP1A2PKMSMN1; SMN2NPSR1 | |
| SCHEMBL4991700 | 0.69 | SMN1; SMN2 (0.57) | CYP2D6CYP1A2SMN1; SMN2CYP2C19LMNA | |
| SCHEMBL9019184 | 0.69 | SMN1; SMN2 (0.57) | CYP2D6CYP1A2SMN1; SMN2CYP2C19LMNA | |
| SCHEMBL1218849 | 0.68 | EPHX1 (0.50) | CYP2D6CYP1A2PKMSMN1; SMN2NPSR1 | |
| SCHEMBL2332933 | 0.68 | EPHX1 (0.50) | CYP2D6CYP1A2PKMSMN1; SMN2NPSR1 | |
| SCHEMBL3262994 | 0.68 | DPP4 (0.48) | LMNAGRM2GRM3HTR2ATAAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110130280-A1 | THERMOREVERSIBLE RECORDING MEDIUM, AND THERMOREVERSIBLE RECORDING MEMBER | RICOH COMPANY, LTD. (JP) | 2011-06-02 | — | — | US | disclosed |