Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 14/20 | 0.81 |
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.81 |
| ▸ | HPGD | P15428 | 8/20 | 0.81 |
| ▸ | GAA | P10253 | 7/20 | 0.81 |
| ▸ | RXFP1 | Q9HBX9 | 7/20 | 0.78 |
| ▸ | MAPT | P10636 | 11/20 | 0.77 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.77 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.74 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.74 |
| ▸ | GLA | P06280 | 3/20 | 0.71 |
| ▸ | TSHR | P16473 | 1/20 | 0.71 |
| ▸ | HTT | P42858 | 3/20 | 0.68 |
| ▸ | USP2 | O75604 | 1/20 | 0.65 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.65 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.65 |
| ▸ | POLB | P06746 | 1/20 | 0.63 |
| ▸ | ATM | Q13315 | 1/20 | 0.61 |
| ▸ | LMNA | P02545 | 1/20 | 0.61 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL427370 | 0.90 | KDM4E (1.00) | KDM4EALDH1A1HPGDGAARXFP1 | |
| SCHEMBL20467123 | 0.82 | KDM4E (0.67) | KDM4EALDH1A1HPGDGAARXFP1 | |
| SCHEMBL23657476 | 0.78 | MEN1 (0.82) | KDM4EALDH1A1HPGDGAARXFP1 | |
| SCHEMBL19805083 | 0.77 | KDM4E (0.80) | KDM4EALDH1A1HPGDGAARXFP1 | |
| SCHEMBL4053028 | 0.77 | KDM4E (0.72) | KDM4EALDH1A1HPGDGAARXFP1 | |
| SCHEMBL14110617 | 0.76 | IKBKB (0.83) | KDM4EALDH1A1HPGDGAARXFP1 | |
| SCHEMBL426279 | 0.75 | KDM4E (1.00) | KDM4EALDH1A1HPGDGAARXFP1 | |
| SCHEMBL14955316 | 0.75 | KDM4E (0.85) | KDM4EALDH1A1HPGDGAARXFP1 | |
| SCHEMBL5013124 | 0.74 | KDM4E (0.73) | KDM4EALDH1A1HPGDGAARXFP1 | |
| SCHEMBL26780451 | 0.74 | KDM4E (0.94) | KDM4EALDH1A1HPGDGAAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110152301-A1 | Compounds that Inhibit HIV Particle Formation | UNIVERSITY OF VIRGINIA PATENT FOUNDATION (US) | 2011-06-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110152301-A1 | Compounds that Inhibit HIV Particle Formation | REV1, VPS51, FLOT1 | KDM4E 3600/4885ALDH1A1 3746/4885HPGD 2465/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.