Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PGR | P06401 | 7/20 | 0.68 |
| ▸ | NR3C1 | P04150 | 7/20 | 0.68 |
| ▸ | HIF1A | Q16665 | 6/20 | 0.68 |
| ▸ | LMNA | P02545 | 2/20 | 0.68 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.68 |
| ▸ | USP2 | O75604 | 1/20 | 0.68 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.68 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.68 |
| ▸ | ABCB11 | O95342 | 2/20 | 0.56 |
| ▸ | ABCC3 | O15438 | 1/20 | 0.56 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.56 |
| ▸ | NR3C2 | P08235 | 5/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.54 |
| ▸ | AR | P10275 | 2/20 | 0.54 |
| ▸ | TNF | P01375 | 1/20 | 0.54 |
| ▸ | IL6 | P05231 | 1/20 | 0.54 |
| ▸ | SERPINA6 | P08185 | 1/20 | 0.54 |
| ▸ | GLUL | P15104 | 1/20 | 0.54 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.54 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12562918 | 0.98 | PGR (0.66) | PGRNR3C1HIF1ALMNACYP3A4 | |
| SCHEMBL12562913 | 0.97 | PGR (0.67) | PGRNR3C1HIF1ALMNACYP3A4 | |
| SCHEMBL12562912 | 0.95 | PGR (0.64) | PGRNR3C1HIF1ALMNACYP3A4 | |
| SCHEMBL12562940 | 0.94 | NR3C1 (0.64) | PGRNR3C1HIF1ALMNACYP3A4 | |
| SCHEMBL13493163 | 0.94 | NR3C1 (0.64) | PGRNR3C1HIF1ALMNACYP3A4 | |
| SCHEMBL12562926 | 0.94 | PGR (0.65) | PGRNR3C1HIF1ALMNACYP3A4 | |
| SCHEMBL12562936 | 0.94 | PGR (0.61) | PGRNR3C1HIF1ALMNACYP3A4 | |
| SCHEMBL13659805 | 0.94 | PGR (0.79) | PGRNR3C1HIF1ALMNACYP3A4 | |
| SCHEMBL12562930 | 0.93 | NR3C1 (0.62) | PGRNR3C1HIF1ALMNACYP3A4 | |
| SCHEMBL12562915 | 0.93 | HIF1A (0.63) | PGRNR3C1HIF1ALMNACYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110130376-A1 | NEW NO RELEASING STEROIDS DERIVATIVES | NICOX S.A. (FR) | 2011-06-02 | — | — | US | disclosed |
| WO-2010015529-A1 | NEW NO RELEASING STEROIDS DERIVATIVES | NICOX S.A. (FR) | 2010-02-11 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110130376-A1 | NEW NO RELEASING STEROIDS DERIVATIVES | CYP11B2, CYP11B1, NR3C2 | PGR 145/4885NR3C1 7/4885HIF1A 1676/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.